Project Grant R21NS141756
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $737,881 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) to conduct secondary analyses of the ACTG IMAGINE-TBM clinical trial. The objectives are to use metagenomics and host transcriptomics to improve diagnosis of tuberculous meningitis (TBM) and assess treatment response in this...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025 for $1,180,687. The purpose of this 8-year project is to investigate how neural stem cell niches transition from embryonic to postnatal stages in the human forebrain, with a focus on characterizing the different neural...
- This Cooperative Agreement, awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research), provides $315,066 in funding to The Regents of the University of California, San Francisco (UCSF) from September 1, 2025 to August 31, 2028. The project aims to validate, translate, and clinically implement a gene expression biomarker to predict outcomes and radiotherapy responses for meningioma, a common type of brain tumor. The research will focus on improving risk...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
- This Project Grant award of $162,756.00 from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) supports research to advance understanding of chromosomal instability and radiation sensitivity in meningioma, the most common primary brain tumor. The key objectives are to: 1) Validate a transcriptomic biomarker to predict meningioma outcomes and identify patients most likely to benefit from radiation therapy; 2) Utilize novel models to define how chromosomal instability drives...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $190,485 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Trustees of Indiana University (Indiana University Indianapolis) on February 4, 2025. The grant supports research to investigate the molecular mechanisms underlying differentiation failure in neuroepithelial stem cells with NF2 gene mutations, with the goal of identifying novel therapeutic...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $125,724 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on January 23, 2025. The project, titled "Hypoxia-Induced Misdirection: Understanding Postnatal Inhibitory Interneuron Migration in Neonatal Hypoxic Injury", aims to use computational approaches to identify altered...
- This federal Project Grant award of $610,554.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to mechanistically link and leverage the interrelated findings on tumor-induced alterations in peritumoral neuronal mTOR and GABAergic signaling. The research aims to understand how these alterations contribute to both tumor-associated seizures and...
- This $198,928 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant will support research at the University of California, San Francisco to elucidate the cellular mechanisms underlying central nervous system injury and progression in multiple sclerosis. Key objectives include determining the role of astrocyte response,...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,500 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Leland Stanford Junior University (Stanford University) on August 1, 2025. The funding will support a research project titled "Defining Mechanisms of Cognitive Dysfunction in Central Nervous System Autoimmunity" through July 31, 2027. The project aims to evaluate the pathogenic...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $209,910 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF) on August 1, 2025. The grant supports a 2-year research project to conduct mechanistic and functional genomic analysis of genes associated with meningioma radiotherapy response. The goal is to better understand the biology of meningiomas, a type of brain tumor, and develop improved risk stratification and treatment approaches. The research leverages UCSF's expertise in neuroscience, cancer research, and translational studies to advance understanding and care for patients with this neurological condition.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $209.9k | 7/28/25 |