Project Grant K08CA304352
Award Date 8/1/26
Completion Date 7/31/31
Dollars Obligated $291K
Federal Agency
Awardee
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New Haven, CT 06511, USA
Similar Awards
- Federal Project Grant Award Summary Yale University received a $696,189 Cancer Biology Research (CFDA 93.396) project grant from the National Cancer Institute, awarded April 7, 2026, with completion scheduled for March 31, 2031. The grant funds fundamental research investigating the mechanisms of CD8 T cell differentiation in tumor-draining lymph nodes (TDLNs) to improve outcomes for lung adenocarcinoma patients undergoing PD-1 pathway-targeted immunotherapy. The research employs genetically...
- Federal Grant Award Summary The National Cancer Institute awarded Yale University a $478,532 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective September 1, 2025, through August 31, 2027. This research initiative will investigate the biological and clinical significance of spatial immune heterogeneity in non-small cell lung cancer (NSCLC), with particular focus on characterizing how the spatial distribution of tumor-infiltrating lymphocytes (TILs) and tertiary...
- Federal Grant Award Summary Yale University received a $684,252 Project Grant from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) effective June 2, 2026, with completion anticipated by May 31, 2031. This research project investigates the functions and mechanisms of innate lymphoid cells type 2 (ILC2s) in trained immunity—a process by which hematopoietic stem and progenitor cells (HSPCs) develop epigenetic memory following inflammatory stimuli such as...
- Federal Grant Award Summary Yale University received a $167,771 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) awarded August 1, 2025, with completion targeted for July 31, 2027. The award supports research to elucidate the mechanisms of a novel human-specific immune checkpoint interaction between SIGLEC-7 and VSIG4 proteins. The research will utilize a humanized mouse platform (MISTRG6-A2) to develop in vivo models that investigate how...
- Federal Grant Award Summary Yale University received a $672,371 Project Grant award from the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research Program (CFDA 93.394), effective September 1, 2025, through August 31, 2028. The grant funds development of ultra-sensitive mass spectrometry-based immunopeptidomics technology utilizing digital microfluidics to identify tumor-specific antigens (TSAs) for cancer immunotherapy applications. The project addresses current...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Yale University a $295,192 Project Grant under the Cancer Research Manpower program (CFDA 93.398) to support research career development and training activities for Dr. Goran Micevic. The grant, which commenced July 1, 2026, and extends through June 30, 2031, funds research and professional development designed to establish Dr. Micevic as an independent investigator in basic and translational tumor immunology,...
- Federal Grant Award Summary Yale University received a $482,312 Project Grant from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) effective April 2, 2026, through March 31, 2031. The award supports research to develop a novel therapeutic approach for inactivating regulatory T (Treg) cells through targeted protein degradation as a strategy to enhance cancer immunotherapy efficacy and reduce immune-related adverse events. Building on promising...
- Federal Grant Award Summary Yale University received a $610,637 Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395), effective April 1, 2026 through March 31, 2031. The award funds research and development of a versatile drug delivery platform utilizing bioadhesive and non-adhesive biodegradable nanoparticles engineered for selective locoregional delivery of cytotoxic and immune conditioning agents to treat advanced melanoma. The...
- Federal Project Grant Award Summary Yale University received a $192,564 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), effective September 1, 2025 through August 31, 2028. The award supports the development of innovative dual-target Protease Targeted Chimera (PROTAC)-based protein degraders designed to overcome therapy resistance in metastatic castration-resistant prostate cancer (MCRPC). The research addresses lineage...
- Federal Grant Award Summary Yale University received a $100,228 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398) awarded December 1, 2026, with completion targeted for August 31, 2029. The grant supports research investigating the regulation of membrane-chromatin interactions during mitotic nuclear envelope (NE) assembly and their implications for cancer cell survival. The project addresses fundamental mechanisms by which endoplasmic...