The National Cancer Institute (NCI) awarded a $662,761 Cooperative Agreement under the Cancer Cause and Prevention Research program (CFDA 93.393) to Dartmouth-Hitchcock Clinic to conduct the "VIDEO-PEDS" project. This project aims to develop and evaluate the impact of a video-based goals-of-care (GOC) decision aid intervention for parents of children with cancer. The funding will support the refinement of the GOC video, infrastructure development, piloting, and a large pragmatic...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $943,540 aims to determine the effects of a Shared Decision Making (SDM) toolkit on mammography use, decision quality, and knowledge in breast cancer survivors aged 80 and older. The SDM toolkit was previously developed under an NCI R21 grant to support clinicians and older women in deciding when to discontinue surveillance mammography, as data suggests limited survival benefit when life...
This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) to Dartmouth-Hitchcock Clinic provides $635,946 to conduct research aimed at understanding the role of melanocyte PD-L1 expression in modulating the immune response to UV-induced melanoma. The key objectives are to: Test the hypothesis that UV-induced interferon-I signaling elicits a PD-L1-dependent inflammatory memory in melanoma, impacting tumor immune surveillance and progression. This will...
This $710,264 federal Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) will fund research at Yale University to quantify patient-provider communication using machine learning. The goal is to assess the impact of effective patient-provider communication on outcomes for metastatic cancer patients, such as adherence to oral therapies and utilization of emergency services. The project will refine a machine learning tool...
This Project Grant award from the National Cancer Institute (NCI) under the Cancer Research Manpower (CFDA 93.398) program will support a multilevel intervention to improve communication between healthcare providers and patients about the use of complementary and alternative medicine (CAM) for cancer treatment. The $388,800 award to HMH Hospitals Corporation, doing business as Hackensack University Medical Center, will be used to: 1) engage providers and patients to develop a CAM-focused...
This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) will fund a research project titled "Interventions to Decrease Cancer Information Avoidance." The total funding amount is $637,596 over the award period from April 4, 2025 to March 31, 2030. The project aims to develop and test a video-based intervention strategy designed to reduce defensive avoidance of colorectal cancer information and increase engagement with...
This $684,333 federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) supports research to evaluate if patient and provider decision support that integrates breast cancer and cardiovascular disease risk assessment can improve the acceptance and uptake of chemoprevention among racially/ethnically diverse women at high risk for breast cancer. The key objectives are to: 1) refine patient-facing and provider-facing decision support tools...
This federal Project Grant award, provided by the National Cancer Institute (NCI) under the Cancer Research Manpower (CFDA 93.398) program, aims to integrate an electronic patient-reported outcomes (PROs) tool called "Goals to Discharge" (G2D) into the discharge planning process for surgical oncology patients at Memorial Sloan Kettering Cancer Center. The $210,014 award, with a project period from July 1, 2024 to June 30, 2029, will enable the principal investigator, Dr. Jennifer...
This National Cancer Institute (NCI) K08 Mentored Career Development Award, under CFDA 93.398 Cancer Research Manpower program, will provide $285,049 to the University of North Carolina at Chapel Hill from June 2024 to May 2029. The award will support Dr. Daniel Richardson's research to develop and evaluate a novel "values elicitation tool" called PRIME to improve shared treatment decision-making for older patients with acute myeloid leukemia (AML). The project aims to (1) determine...
This Project Grant award, valued at $496,567 and awarded by the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) on June 1, 2024, will support research to develop, validate, and implement advanced computational tumor phenotyping techniques to characterize head and neck squamous cell carcinoma (HNSCC) at multiple biological levels. The research involves high-throughput analysis of quantitative features from radiology images (radiomics) and digital pathology images...