Project Grant K08AI193234
Award Date 8/1/25
Completion Date 7/31/30
Dollars Obligated $189K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
- This federal Project Grant award of $208,332 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to advance understanding of how Staphylococcus aureus, a leading global pathogen, causes spine infections in humans. The award to New York University School of Medicine will support research to evaluate the contributions of specific S. aureus virulence factors in enabling the pathogen to evade the human immune system and cause...
- This Project Grant award, titled "Bacterial Cell Wall Remodeling, Innate Immunity, and Pathogenesis", is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The $2,841,668 award will support research conducted by the University of Illinois to investigate how the staphylococcal N-acetyl glucosaminidase B (SagB) enzyme modulates the host immune response to Staphylococcus aureus infections....
- This $226,253 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand how the host protein ADAM10 modulates the interactions between neutrophils and the endothelium during Staphylococcus aureus infection. The project aims to generate a spatiotemporal analysis of these key cellular and molecular interactions in the early stages of infection, leveraging...
- The University of South Florida (USF) received a $480,522 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports research to investigate the regulation and role of the secreted proteases of the bacterium Staphylococcus aureus, a major cause of infectious disease. The research aims to elucidate how these enzymes mediate S. aureus pathogenesis and virulence, with...
- This Project Grant award of $115,123 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to reveal strategies for eradicating antibiotic-tolerant Staphylococcus aureus persister cells. The research aims to identify the host cells harboring intracellular S. aureus reservoirs and characterize the host and bacterial transcriptomes using single-cell approaches. Additionally, the project...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a $638,953 Project Grant to Abvacc, Inc., a biotechnology company in Rockville, Maryland. The grant, running from August 2025 to July 2030, supports the development of an immunotherapeutic antibody cocktail for the treatment of Staphylococcus aureus bacteremia (SAB). The project aims to target multiple mechanisms of growth and immune...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $390,000 to support research on the molecular basis of Staphylococcus aureus SPLB manipulation of the host. The research aims to: 1) identify host protein targets of S. aureus SPLB, 2) elucidate how SPLB-target interactions induce conformational changes, and 3) determine how N-terminal cleavage activates the...
- This $420,553 federal Project Grant award was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant aims to develop a single-cell technique that will measure the translation rate and transcriptome of thousands of individual bacterial cells, with a focus on understanding antibiotic tolerance in Staphylococcus aureus during chronic infections. The research will explore the heterogeneity in...
- The University of South Florida (USF) received a $470,953 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant funding supports research to determine the role and regulation of the regulatory RNA SSR42 in virulence factor regulation in Staphylococcus aureus (S. aureus). The research aims to characterize how SSR42 impacts S. aureus virulence, including effects on hemolytic...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $3,121,542 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to The Johns Hopkins University. The purpose of this 4-year project, starting on August 1, 2025, is to develop and utilize animal models and novel positron emission tomography (PET) imaging techniques to study Staphylococcus aureus (S. aureus) orthopedic implant-associated infections. This research aims to...