Project Grant R01AI193221
Award Date 8/22/25
Completion Date 7/31/30
Dollars Obligated $639K
Federal Agency
Awardee
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Maryland, USA
Similar Awards
- The Project Grant award of $188,916 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research by Brigham & Women's Hospital Inc. (a subsidiary of Partners Healthcare System) to investigate how the bacterium Staphylococcus aureus evades detection and clearance by the immune system. The research aims to determine how noncytotoxic (non-harmful) strains of S. aureus restrict immune...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $189,558 to Duke University to identify genomic determinants of antibiotic treatment failure in Staphylococcus aureus bacteremia (SAB). The primary objectives are to: 1) Use a murine in-vivo evolution model to identify bacterial genotypes associated with SAB treatment failure, and 2) Conduct a genome-wide...
- This $4,776,780 Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to advance promising multicomponent vaccines for the bacterial pathogens Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. The overarching goals are to develop novel multivalent vaccines that provide broad, serotype-independent protection against these resistant and multidrug-resistant infections,...
- This Project Grant award of $3,121,542.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development of animal models and novel positron emission tomography (PET) bioimaging techniques to study Staphylococcus aureus orthopedic implant-associated infections. The research aims to replicate key pathological features of the human disease and enable longitudinal, non-invasive measurements...
- This federal Project Grant award of $417,845 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to identify novel immune determinants that influence Staphylococcus aureus (S. aureus) biofilm infection. The research will leverage the genetically diverse Collaborative Cross mouse model to better understand how host genetic factors contribute to the heterogeneity observed in immune...
- This $2,841,668 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research on bacterial cell wall remodeling, innate immunity, and pathogenesis related to Staphylococcus aureus infections. The award aims to improve understanding of how peptidoglycan recognition and modification by the S. aureus enzyme SagB shape inflammatory immune responses, including IL-1β production, and infection...
- The Project Grant award titled "ROLE AND REGULATION OF THE SECRETED PROTEASES OF STAPHYLOCOCCUS AUREUS" is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855). The $480,522 award, granted on July 23, 2025, supports research to understand the role and regulation of the secreted proteases of Staphylococcus aureus. The project aims to dissect the regulation of these enzymes and explore their...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research into the role of the SSR42 regulatory RNA in virulence factor regulation in Staphylococcus aureus. The $470,953 award, made on August 1, 2025, will fund a 5-year research project at the University of South Florida to characterize how SSR42 regulates numerous secreted virulence factors central to S. aureus infection. Key...
- This $115,123 federal Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) on Aug 20, 2025. The grant supports research conducted by the University of North Carolina at Chapel Hill (UNC-CH) to investigate strategies for eradicating intracellular Staphylococcus aureus (S. aureus) persisters, which can lead to recurring antibiotic-resistant infections. The key products and services to...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) provides $208,332.00 to New York University to conduct research on host-pathogen interactions during Staphylococcus aureus spine infections. The research aims to define the molecular mechanisms underlying the severe disease morbidity and mortality associated with these spine infections, which can lead to paralysis in up to 75% of patients and up to...