This Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the influence of the cervicovaginal phageome (bacteriophages) on women's reproductive health, particularly in the context of HIV/AIDS. The $196,452 award, effective August 7, 2024 through July 31, 2028, will utilize metagenomic sequencing to study the FRT phageome communities over time, the impact of AIDS and antiretroviral therapy on the phageome, and identify predictive biomarkers of shifts in the FRT bacteriome that can lead to reproductive tract diseases. The ultimate goal is to improve understanding of bacteriophage-bacterial interactions in the female reproductive tract, which could inform the development of novel preventative strategies and phage-based therapeutics for conditions like bacterial vaginosis and sexually transmitted infections, thereby enhancing women's reproductive health.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $196.5k | 8/7/24 |