This $1,127,000 federal Project Grant award from the National Institutes of Health (NIH) Office of the Director's Trans-NIH Research Support program (CFDA 93.310) will fund a transformative research program at Duke University to map and dissect the brainstem neural circuits that coordinate orofacial rhythmic movements such as licking, breathing, and swallowing. The research aims to shed light on the neural mechanisms underlying these critical life functions and how they may be impacted in...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), part of the Oral Diseases and Disorders Research program (CFDA 93.121), provides $738,929 to The Trustees of Columbia University in the City of New York to develop and validate a patient-specific TMJ-on-a-chip (TMJOC) model. The TMJOC will be used to investigate multi-tissue crosstalk regulating temporomandibular joint (TMJ) disc injury and healing under inflammation and pathophysiological...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, is focused on studying the role of the SIX1 transcription factor in cell fate decisions within the mouse mandibular arch. The total funding amount is $315,289, with a project period from July 15, 2025 to July 14, 2027. The key objectives of this award are to: 1) Identify changes in cell populations within the mouse mandibular arch...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to determine the function of TRP-positive trigeminal sensory neurons innervating the submandibular salivary glands. The $174,418 award to the Regents of the University of Michigan will support research to understand how this direct sensory innervation provides feedback to modulate the salivary system, with the goal of...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,325,889 Project Grant under the Oral Diseases and Disorders Research (CFDA 93.121) program to the University of Southern California on September 19, 2024. This grant, titled "Regulating Skeletal Connectivity in Craniofacial Development and Disease," will support a comprehensive and forward-thinking research program led by Dr. Amy Merrill that investigates the craniofacial skeleton as a multi-tissue...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program, provides $688,679 to the University of Southern California (USC) to conduct innovative research mapping the transcriptomes and lineage relationships of cell types in the developing vertebrate face. The goal is to develop new technology capable of uniquely labeling and permanently tracing the lineages of all cells...
The National Institute of Dental and Craniofacial Research (NIDCR) has awarded a $148,176 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Regents of the University of California, Berkeley. The funding will support research to uncover novel gene regulatory networks underlying craniofacial development and specialization in pupfish species. The project aims to leverage the unique evolutionary model of Cyprinodon pupfishes on San Salvador Island to...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), part of the Oral Diseases and Disorders Research program (CFDA 93.121), provides $628,965.00 to the Icahn School of Medicine at Mount Sinai over a 5-year period from May 1, 2025 to April 30, 2030. The funding supports research to elucidate how immune cells, specifically tissue-resident macrophages, regulate the coordinated processes of salivary gland development and differentiation. The...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372), provides funding to Cornell University to study the neural mechanisms underlying sensorimotor control of the tongue. The 5-year, $104,571 award will support research to quantify tongue kinematics and identify the neural signals and circuits that underlie...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121), is providing $100,676 to the Icahn School of Medicine at Mount Sinai to conduct research on defining the role of tissue-resident macrophages during salivary gland morphogenesis. The research aims to determine the functional contribution of these macrophages to salivary gland development and characterize their role in...