Project Grant HT9425261E429
- Federal Project Grant Award Summary Duke University's Office of Research Administration has been awarded $489,987 by the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for a three-year project beginning September 1, 2026, and concluding August 31, 2029. The project, titled "Metastasis-Initiating Cells and Lung Repair as Drivers of Metastasis in Undifferentiated Pleomorphic Sarcoma (UPS): Biologic and Therapeutic Implications," will...
- Federal Project Grant Award Summary Award: The Defense Health Agency (DHA), through its Military Medical Research and Development program (CFDA 12.420), awarded Duke University's Office of Research Administration a Project Grant of $564,705 on September 15, 2025, for research extending through September 14, 2028. The award supports the identification of oncofusion-interacting proteins as essential drug targets for common and rare oncofusions in rhabdomyosarcoma. This research initiative aligns...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1.54M project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds research activities focused on assessing prognoses and validating surrogate endpoints for clinical outcomes in metastatic hormone-sensitive prostate cancer. This research initiative aligns with the Defense...
- Federal Project Grant Award Summary Duke University's Office of Research Administration was awarded $490,000 by the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct a three-year project beginning September 1, 2026, and concluding August 31, 2029. The project, titled "Genotype-Phenotype Modeling of Rare Sinonasal Tumors to Enable Precision Oncology," will deliver research services focused on developing computational and...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $700,032 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025, through July 31, 2029. The award supports research titled "Imaging Strategies and Biomarkers for Detecting the Metabolic Interplay of Glutamine and Aspartate in RCC" (Renal Cell Carcinoma), with work performed at Duke's Durham,...
- Federal Project Grant Award Summary Duke University's Office of Research Administration was awarded $845,250 by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) beginning July 1, 2025, through June 30, 2028. The project focuses on engineering T-cell receptor (TCR)-modified T cells designed to target human endogenous retroviruses for non-small cell lung cancer immunotherapy. This research initiative represents an advanced biomedical research...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded Duke University's Office of Research Administration a $696,154 Project Grant on September 1, 2026, under the Military Medical Research and Development program (CFDA 12.420) to conduct a three-year investigation through August 31, 2029. This research initiative, titled "Off-Target Effects of Breast Cancer Adjuvant Radiation Therapy on Thymus Function in Young Women," is designed to examine the unintended...
- Federal Project Grant Award Summary Duke University's Office of Research Administration is conducting a three-year research project funded by the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) with a total obligation of $553,848. The project, titled "Off-Target Effects of Breast Cancer Adjuvant Radiation Therapy on Thymus Function in Young Women," commenced on September 1, 2026, and will conclude on August 31, 2029. The research...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1,992,959 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) on September 30, 2026. The award funds the establishment and operation of the PCRP (Prostate Cancer Research Program) Clinical Consortium as a clinical research site located in Durham, North Carolina, with a performance period extending through September...
- Federal Grant Award Summary Award Details: The University of North Carolina at Chapel Hill received a $749,996 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) on August 1, 2026, with an ultimate completion date of July 31, 2029. The research will be performed at UNC-Chapel Hill's Chapel Hill, NC location through the Office of Sponsored Research. Project Scope: This award funds basic and applied biomedical research...
Duke University's Office of Research Administration received a $139,881 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) on September 1, 2026. The research project, titled "Investigating Tumor-Osteoclast Interactions in the Chondrosarcoma Microenvironment and Its Effect on Metastatic Disease Progression," will be conducted in Durham, North Carolina, with a completion date of August 31, 2028. This investigator-initiated research initiative will deliver fundamental biomedical research findings examining the mechanisms of tumor-osteoclast cellular interactions within chondrosarcoma (a bone cancer) and their relationship to metastatic disease progression, which has direct relevance to advancing medical solutions for Service Member health and cancer treatment. The award supports basic and applied research activities aligned with the Defense Health Agency's mission to transform healthcare through innovative biomedical research. Duke University, a recognized leader in oncology and cancer research with substantial federal research infrastructure, will execute this two-year investigation to generate data on tumor microenvironment dynamics that may inform future therapeutic development strategies for managing chondrosarcoma and reducing its metastatic potential.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $139.9k | 7/23/26 |