Project Grant HT9425261E394
- Federal Project Grant Award Summary Award: The Defense Health Agency (DHA), through its Military Medical Research and Development program (CFDA 12.420), awarded Duke University's Office of Research Administration a Project Grant of $564,705 on September 15, 2025, for research extending through September 14, 2028. The award supports the identification of oncofusion-interacting proteins as essential drug targets for common and rare oncofusions in rhabdomyosarcoma. This research initiative aligns...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1.54M project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds research activities focused on assessing prognoses and validating surrogate endpoints for clinical outcomes in metastatic hormone-sensitive prostate cancer. This research initiative aligns with the Defense...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $700,032 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025, through July 31, 2029. The award supports research titled "Imaging Strategies and Biomarkers for Detecting the Metabolic Interplay of Glutamine and Aspartate in RCC" (Renal Cell Carcinoma), with work performed at Duke's Durham,...
- Federal Project Grant Award Summary Duke University's Office of Research Administration was awarded $845,250 by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) beginning July 1, 2025, through June 30, 2028. The project focuses on engineering T-cell receptor (TCR)-modified T cells designed to target human endogenous retroviruses for non-small cell lung cancer immunotherapy. This research initiative represents an advanced biomedical research...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded Duke University $696,154 under the Military Medical Research and Development program (CFDA 12.420) to investigate off-target effects of breast cancer adjuvant radiation therapy on thymus function in young women. The three-year project, initiated September 1, 2026 and concluding August 31, 2029, will be conducted at Duke University's Durham, North Carolina facility. The research addresses a critical gap in understanding...
- Federal Project Grant Award Summary Duke University's Office of Research Administration was awarded $960,626 by the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to investigate NUAK2 as a novel splicing regulatory kinase in neuroendocrine prostate cancer. The two-year project, initiated August 1, 2025 and concluding July 31, 2027, will be conducted at Duke's Durham, North Carolina location. This award supports investigator-initiated...
- Federal Grant Award Summary Duke University's Office of Research Administration received a $553,848 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2026 through August 31, 2029. The project, titled "Off-Target Effects of Breast Cancer Adjuvant Radiation Therapy on Thymus Function in Young Women," will investigate the unintended immunological consequences of radiation therapy in female...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $1.99M Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) on September 30, 2026. The award supports the establishment and operation of the Prostate Cancer Research Program (PCRP) Clinical Consortium Duke University Clinical Research Site, with a performance period through September 29, 2030. This clinical research...
- Federal Grant Award Summary The University of North Carolina at Chapel Hill received a $749,996 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective August 1, 2026, through July 31, 2029. The project, titled "Mapping Histologic and Molecular Divergence in Breast Cancer Metastasis," supports biomedical research investigating breast cancer progression and metastatic mechanisms. This three-year research initiative...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded Duke University a $240,897 Project Grant on August 1, 2025, under the Military Medical Research and Development program (CFDA 12.420) to conduct integrative transcriptomic and epigenomic profiling of subependymal giant cell astrocytoma (SEGA) at single-cell resolution. The project, which runs through July 31, 2027, will be performed at Duke University's Office of Research Administration in Durham, North Carolina, under...
Duke University's Office of Research Administration received a $489,987 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 1, 2026 through August 31, 2029. The award funds research investigating metastasis-initiating cells and lung repair mechanisms as drivers of metastasis in undifferentiated pleomorphic sarcoma (UPS), with the aim of developing biologic and therapeutic implications for this rare cancer. Research activities will be conducted at Duke University's Durham, North Carolina facility. This three-year project contributes to the DHA's broader mission to advance biomedical research addressing Service Member health and battlefield medicine. The project represents investigator-initiated research within the Military Medical Research and Development program's portfolio, which supports basic, applied, and advanced research across oncology, rare cancers, and other conditions affecting the military population. Duke University, as a leading research institution with substantial experience managing federal research awards, will execute the research protocol and deliver scientific findings to advance understanding of sarcoma metastasis mechanisms.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $490.0k | 7/15/26 |