This $476,999 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports the Mayo Clinic's research on targeting the AXL receptor tyrosine kinase with a humanized anti-AXL monoclonal antibody as a novel therapy for ovarian cancer. The 4-year project aims to develop and evaluate this antibody-based treatment for ovarian cancer. As a leading non-profit academic medical center, Mayo Clinic leverages its expertise in...
The Defense Health Agency has awarded a $968,400 Project Grant to Mayo Clinic to develop a personalized approach to treating drug-resistant ovarian cancer. The grant, which began on June 1, 2024, and will run through May 31, 2028, is funded under the Military Medical Research and Development program (CFDA 12.420). This program supports biomedical research to improve the health and care of military service members, veterans, and their families. Through this award, Mayo Clinic will leverage its...
This federal Project Grant award from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) provides $3,291,419.00 to Mayo Clinic Arizona to conduct a Phase 1 clinical trial using autologous, MUC1-activated T cells expanded from peripheral blood in patients with relapsed and resistant ovarian cancer. The award period runs from September 1, 2024 to August 31, 2028. This research aims to advance innovative cellular immunotherapy approaches to transform...
The Defense Health Agency awarded a $408,467 Project Grant to Mayo Clinic Arizona, doing business as Mayo Clinic Hospital, for a research project titled "METABOLIC REPROGRAMMING OF CAR MACROPHAGES FOR OVARIAN CANCER IMMUNOTHERAPY." The award period runs from September 1, 2023, to August 31, 2025, under the Military Medical Research and Development (CFDA 12.420) federal grant program. The project aims to study the metabolic reprogramming of chimeric antigen receptor (CAR) macrophages to...
This federal Project Grant award of $1,782,155.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research conducted by the Mayo Clinic to identify novel drug targets for lethal prostate cancer using liquid biopsy techniques. The award period runs from April 1, 2025 to March 31, 2028. The research aims to transform healthcare for military service members, veterans, and the broader public by advancing innovative biomedical investigations...
The Defense Health Agency awarded a $597,543.00 Project Grant to Mayo Clinic Arizona, doing business as Mayo Clinic Hospital, a nonprofit academic medical center. The grant, which runs from October 1, 2023 to September 14, 2026, is funded under the Military Medical Research and Development program (CFDA 12.420) to support research aimed at "elucidating mechanisms of CAR-T cell immunotherapy resistance and sensitivity to improve treatment of myeloma." As a nonprofit organization with...
This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $564,900.00 to Mayo Clinic to support research aimed at "EXPLOITING VIRAL TROPISM TO TARGET CANCER-ASSOCIATED FIBROBLASTS IN INTRAHEPATIC CHOLANGIOCARCINOMA". The award period runs from September 1, 2024 to August 31, 2026. Mayo Clinic, a renowned non-profit academic medical center, will leverage its expertise in cancer biology, drug development,...
The Mayo Clinic will identify novel protein biomarkers and targets to overcome PARP inhibitor resistance under a $954,000 project grant from the Department of the Army Medical Command. The grant was awarded on June 15, 2021 with a completion date of June 14, 2025 under the Military Medical Research and Development program (CFDA 12.420). This program supports basic, applied, and advanced biomedical research to transform military and public health care through innovative medical solutions for...
Mayo Clinic was awarded a $8,966,819 project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant will support research from July 1, 2023 to June 30, 2027 to further develop purified exosome products for treating pulmonary damage from toxic exposures, leveraging Mayo Clinic's expertise in exosome applications. Through this funding, Mayo Clinic aims to advance biomedical solutions applicable to both military and civilian...
The federal Project Grant award of $161,400.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) will support Mayo Clinic's research project titled "AN ATLAS OF THE TUMOR IMMUNE CIRCULOME." This award, with a performance period from June 1, 2024 to May 31, 2025, aims to advance medical knowledge and improve patient care through innovative biomedical research. The Military Medical Research and Development program funds a wide range of...