The Defense Health Agency awarded a $597,543.00 Project Grant to Mayo Clinic Arizona, doing business as Mayo Clinic Hospital, a nonprofit academic medical center. The grant, which runs from October 1, 2023 to September 14, 2026, is funded under the Military Medical Research and Development program (CFDA 12.420) to support research aimed at "elucidating mechanisms of CAR-T cell immunotherapy resistance and sensitivity to improve treatment of myeloma." As a nonprofit organization with...
This federal Project Grant award, issued by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, provides $3,291,419.00 to Mayo Clinic Arizona to conduct a Phase 1 clinical trial using autologous, MUC1-activated T cells expanded from peripheral blood in patients with relapsed and resistant ovarian cancer. The award period runs from Sep 1, 2024 to Aug 31, 2028. The project aims to explore innovative immunotherapy approaches to treat this challenging...
The Defense Health Agency has awarded a $968,400 Project Grant to Mayo Clinic to develop a personalized approach to treating drug-resistant ovarian cancer. The grant, which began on June 1, 2024, and will run through May 31, 2028, is funded under the Military Medical Research and Development program (CFDA 12.420). This program supports biomedical research to improve the health and care of military service members, veterans, and their families. Through this award, Mayo Clinic will leverage its...
The Department of the Army Medical Command awarded Mayo Clinic Arizona a $1,046,077 Project Grant under the Military Medical Research and Development program (CFDA 12.420). The grant will support research from July 2021 through July 2025 to enhance antitumor immunity with PP4 inhibition and chemoimmunotherapy. Through this funding, Mayo Clinic researchers will investigate medical solutions for the battlefield by transforming health care for service members and the public through innovative and...
The U.S. Defense Health Agency awarded a $2,124,536 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to Mayo Clinic to conduct a clinical evaluation of combination immunotherapy for renal cell carcinoma (RCC). This 3-year project, running from August 2024 to August 2027, will leverage Mayo Clinic's expertise in cancer research and drug development to advance promising immunotherapies for treating RCC. The award will support preclinical pharmacokinetic and...
This $795,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports Mayo Clinic's research to develop a humanized anti-AXL monoclonal antibody as a novel therapy for ovarian cancer. The 4-year project aims to target the AXL receptor tyrosine kinase as a potential new treatment approach. As an experienced biomedical research institution, Mayo Clinic will leverage its expertise in preclinical pharmacokinetic...
This $476,999 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports the Mayo Clinic's research on targeting the AXL receptor tyrosine kinase with a humanized anti-AXL monoclonal antibody as a novel therapy for ovarian cancer. The 4-year project aims to develop and evaluate this antibody-based treatment for ovarian cancer. As a leading non-profit academic medical center, Mayo Clinic leverages its expertise in...
The Department of the Army Medical Command awarded a $1,152,750 project grant to Mayo Clinic under the Military Medical Research and Development program (CFDA 12.420). The grant will fund research from June 2021 to June 2025 to decipher the role of cancer stem cells in chemotherapy resistance in high grade serous carcinoma. Through this funding, Mayo Clinic researchers will investigate medical solutions for chemotherapy resistance on the cellular level to help transform health care for service...
The U.S. Defense Health Agency awarded a $1,665,000 Project Grant (CFDA 12.420 - Military Medical Research and Development) to Mayo Clinic Arizona, a subsidiary of Mayo Collaborative Services, Inc., for research on "PATHOGENESIS, DIAGNOSIS, AND TREATMENT OF CARDIOVASCULAR FAILURE IN ACUTE PANCREATITIS". The 4-year grant, effective January 1, 2025 through December 31, 2028, will support advanced biomedical research to transform healthcare for military service members and the general...
The Defense Health Agency awarded Mayo Clinic Jacksonville $3,232,027 under the Military Medical Research and Development federal grant program (CFDA 12.420) from September 15, 2023 through September 14, 2027. Through this award, Mayo Clinic will integrate molecular pathology, radiology, and genetics to improve breast cancer risk prediction. The Military Medical Research and Development program supports basic, applied, and advanced biomedical research to transform health care for service members...