Project Grant HT94252310367

This $462,131 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports transformative behavioral health research to improve quality of life for individuals with childhood-onset lupus. The prime awardee, The Hospital for Sick Children (Sick Kids Hospital) in Toronto, Canada, will lead this 4-year initiative. As a leading pediatric research hospital, Sick Kids Hospital has extensive experience as a subcontractor on...

The University of California, San Francisco will conduct research on NR4A family proteins as markers and mediators of B cell tolerance in systemic lupus erythematosus (SLE) under a three-year, $738,631 Project Grant from the Department of the Army Medical Command. The grant is part of the Military Medical Research and Development program administered by the Department of Defense and aims to transform military and public health through innovative medical research solutions for battlefield...

This Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $115,414 to the Beckman Research Institute of the City of Hope to conduct research aimed at concurrently eradicating pathogenic plasma cells and their precursors in systemic lupus erythematosus (SLE). The award, which runs from September 2024 to August 2026, will support two specific aims: 1) determining the effect of knockdown of the...

Federal Project Grant Summary Boston Children's Hospital received a $905,875 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 19, 2026, with completion targeted for April 30, 2031. The grant funds research to elucidate the genetic mechanisms underlying B cell activation dysregulation in systemic lupus erythematosus (lupus), a leading cause of morbidity among youth in the...

Grant Award Summary The Feinstein Institutes for Medical Research received a $209,375 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded April 23, 2026, with completion targeted for March 31, 2028. The research investigates the role of autophagy in B cell tolerance loss, specifically examining how autophagy defects contribute to systemic lupus erythematosus (SLE) through...

This Project Grant award of $434,993 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to Children's Hospital Los Angeles. The funding supports research using high-throughput sequencing of the immunoglobulin loci to develop refined risk stratification methods for pediatric B-cell acute lymphoblastic leukemia (B-ALL). The project aims to advance understanding and treatment of this pediatric cancer, with an expected completion...

The Defense Health Agency awarded a $1,000,000 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Children's Hospital Corporation, doing business as Boston Children's Hospital, to support research on the "Diversity of Memory B Cells in Lupus". The 4-year grant, with a period of performance from September 1, 2024 to August 31, 2028, will enable Boston Children's Hospital to conduct biomedical research focused on understanding the role of...

Award Summary Yale University received a $462,052 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 19, 2026, with a completion date of January 31, 2028. The award funds research investigating the role of Erythroblast Transformation Specific 2 (ETS2), a transcription factor, in mediating monocyte activation associated with systemic lupus erythematosus (SLE). The...

The University of Pittsburgh received a $499,175 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 1, 2026, through March 31, 2031. This five-year award funds basic and translational research aimed at understanding the genetic and functional characteristics of tissue-infiltrating and age-associated B cells (ABCs) in murine lupus models. The research will dissect how...

Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $929,095 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the La Jolla Institute for Immunology on June 2, 2026, for research extending through May 31, 2031. The award funds a novel research initiative to characterize lymphoid tissue immunology in Systemic Lupus Erythematosus (SLE) patients using minimally invasive nasal swab sampling combined...