Project Grant DP5OD039455
- This National Science Foundation (NSF) Project Grant, awarded under the Biological Sciences program (CFDA 47.074), provides $750,000 to Stanford University to develop new technologies for studying RNA, the essential molecules that carry genetic information and play crucial roles in cell functions. The key products and services to be delivered under this 3-year award include: Creating non-destructive methods to directly study RNA localization and interactions within living cells, achieving...
- This federal Project Grant award of $462,119, granted on September 8, 2025, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports a research project led by The Leland Stanford Junior University (Stanford University) to develop a new live-cell imaging technology called "Transposon Accelerated Chromatin Kinetic Imaging Technology" (TRACK-IT). This technology aims to enable...
- This federal Project Grant award of $459,250.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to develop a systematic approach for detecting regulatory RNAs and their functional motifs based on RNA-protein interactions. The key research objectives include: Investigating whether RNA regulates the genomic occupancies of chromatin-associated proteins (CAPs). Employing an...
- This federal Project Grant award of $308,799, provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), supports research to integrate 4DN data with transcriptome data from the Undiagnosed Disease Network (UDN) and Genotype-Tissue Expression (GTEx) Project. The goal is to leverage 3D genomic information to identify functional rare genetic variants that contribute to rare diseases. The Leland Stanford Junior University, a leading research...
- The National Institute of General Medical Sciences (NIGMS) awarded a $410,256 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Leland Stanford Junior University (Stanford University). This 5-year grant, effective September 15, 2025, aims to integrate physics-based modeling with artificial intelligence to enhance conformational sampling and design of biomolecules, with a focus on understanding self-organization dynamics in biological systems away from...
- This federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) provides $699,999 to researchers at Indiana University School of Medicine to develop computational methods for accurately predicting how chemical modifications to RNA molecules affect their binding and interactions with regulatory proteins. The goal is to advance a physics-based molecular modeling technique called μ-dynamics to model the free energies...
- This Project Grant award from the Trans-NIH Research Support program, CFDA #93.310, provides $1,350,770 to The Leland Stanford Junior University to develop a novel class of synthetic RNA-based receptors to enhance the targeting precision of mRNA-mediated adoptive cell therapies. The project aims to create a modular, programmable receptor system that can convert ligand-induced dimerization events into the expression of desired output proteins, enabling improved specificity for ablating target...
- This $300,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences will support research into the structural biology of RNA and RNA-protein interactions through May 2024. Funded under the Biological Sciences program (CFDA 47.074), this award to Vanderbilt University will utilize joint cryo neutron/x-ray crystallography techniques to better understand the importance of the 2'-hydroxyl group in RNA's expanded three-dimensional structure compared to DNA....
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $2,117,247.00 to The Leland Stanford Junior University (Stanford University) to support research on the genetic basis of complex traits from yeast to humans. The research aims to uncover the evolutionary origins of complex polygenic traits, which underlie most human diseases, by leveraging high-throughput precision genome...
- The National Science Foundation (NSF) Division of Chemistry awarded a $1,500,000 Project Grant to Stanford University under the Mathematical and Physical Sciences (MPS) program (CFDA 47.049). The grant, awarded on March 1, 2024, supports a 3-year research project titled "Evaluating and Advancing Cryo-EM for RNA Conformational Ensembles." The project aims to: (1) design, model, and experimentally probe RNA systems with discrete conformational states, and (2) characterize and challenge...
The Project Grant award, valued at $384,999 and provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), supports a research project conducted by The Leland Stanford Junior University (Stanford University). The project aims to address significant challenges in understanding RNA structure and its critical biological roles through a three-pronged approach: The project has a performance period from August 6, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $385.0k | 8/6/25 |