Project Grant R01GM157292
- This federal Project Grant award of $380,070.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project titled "ACTIVE CHROMOSOME MOVEMENT IN MEIOTIC PAIRING" at the University of California, San Francisco (UCSF). The project aims to investigate the cellular mechanism of meiotic pairing, testing hypotheses regarding the role of telomere-led active motion and nuclear...
- The National Institute of General Medical Sciences (NIGMS) awarded a $410,256 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Leland Stanford Junior University (Stanford University). This 5-year grant, effective September 15, 2025, aims to integrate physics-based modeling with artificial intelligence to enhance conformational sampling and design of biomolecules, with a focus on understanding self-organization dynamics in biological systems away from...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $2,117,247.00 to The Leland Stanford Junior University (Stanford University) to support research on the genetic basis of complex traits from yeast to humans. The research aims to uncover the evolutionary origins of complex polygenic traits, which underlie most human diseases, by leveraging high-throughput precision genome...
- This federal Project Grant award of $308,799, provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), supports research to integrate 4DN data with transcriptome data from the Undiagnosed Disease Network (UDN) and Genotype-Tissue Expression (GTEx) Project. The goal is to leverage 3D genomic information to identify functional rare genetic variants that contribute to rare diseases. The Leland Stanford Junior University, a leading research...
- This federal Project Grant award of $436,001 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), aims to create a novel spatial transcriptomics platform that increases accessibility and efficiency. The key products and services to be delivered include: Developing a spatial transcriptomics platform using a simple filter array format that increases sequencing depth per spatial barcode, enabling more data per...
- The Project Grant award, valued at $384,999 and provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), supports a research project conducted by The Leland Stanford Junior University (Stanford University). The project aims to address significant challenges in understanding RNA structure and its critical biological roles through a three-pronged approach: Developing computational tools, including an RNA sequence database (RNAMASS) and a novel...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant totaling $1,385,226 to The Leland Stanford Junior University (Stanford University) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, spanning from September 1, 2023 to August 31, 2026, will support research to map and therapeutically hijack the trafficking of extracellular proteins to the lysosome, a key cellular process involved in regulating cell surface protein function,...
- This federal Project Grant award of $1,033,055.00 was provided by the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The funding supports research aimed at understanding and targeting the mechanisms of cancer metastasis. The project, titled "Targeting Cancer Metastasis by Inhibiting Curvature-Induced Kinase Activation," seeks to unravel the molecular pathways underlying how cancer cells acquire the...
- This $1,977,264 federal Project Grant, awarded by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel multimodal imaging platform that combines fluorescence super-resolution and tomographic polarized light imaging. The project will create open-source computational imaging tools to recover the dielectric tensor in multiple scattering samples using...
- This $1,737,000 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of innovative single-cell genomics technologies for joint analysis of regulatory dynamics and transcriptional states. Key objectives include: Developing multiomics tools to measure rates of epigenomic changes (DNA methylation, demethylation, oxidative damage, DNA repair) and relate these to...
This federal Project Grant award of $462,119, granted on September 8, 2025, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports a research project led by The Leland Stanford Junior University (Stanford University) to develop a new live-cell imaging technology called "Transposon Accelerated Chromatin Kinetic Imaging Technology" (TRACK-IT). This technology aims to enable high-resolution, high-speed imaging of 3D genome motion to better understand the relationship between genomic organization, transcriptional regulation, and developmental and health/disease processes. The project will investigate 3D genome dynamics at two model loci and test proposed molecular determinants of genome motion through genetic and pharmacological perturbations. The research seeks to advance fundamental scientific understanding in this area, with potential long-term implications for human health. The project is scheduled for completion by July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $462.1k | 9/5/25 |