Project Grant DP2HL185100
- The National Institute of General Medical Sciences (NIGMS) awarded a $408,367 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), under the Biomedical Research and Research Training program (CFDA 93.859). The grant, with a performance period from August 15, 2025 to June 30, 2029, supports research to define an RNA-independent mechanism for the nucleation of heterochromatin formation, a critical process for maintaining genomic stability....
- This federal Project Grant award for $412,500.00, provided by the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 - Biomedical Research and Research Training program, supports a research program to improve the interpretation of rare genetic variants. The awardee, The General Hospital Corporation doing business as Massachusetts General Hospital (MGH), will use state-of-the-art computational methods to enhance existing annotation tools for predicting the impact of...
- The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), was awarded a $577,094 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct research aimed at "Redirecting Viral Immunity to Eradicate Low Tumor Mutation Burden Lung Cancers." The award period runs from Aug 31, 2023 to Aug 29, 2025. As a leading academic medical center and research institution, MGH utilizes its...
- This $453,750 Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports a research project led by The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to investigate the crosstalk between one-carbon metabolism, S-adenosyl-methionine (SAM) availability, and chromatin methylation. The project aims to provide innovative insights into how cells...
- The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), has been awarded a $1,000,236.00 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420). The grant, effective April 1, 2024 through March 31, 2028, will fund research to "UNLOCK THE CTDNA MUTATIONAL PATTERNS FOR EARLY CANCER DETECTION AND NONINVASIVE BIOMARKERS." As a leading academic medical center and research...
- The federal Project Grant award of $992,302 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), located in Boston, MA. This grant, awarded on September 15, 2025, supports advanced biomedical research aimed at "Targeting MHCII Ubiquitination to Induce Immune Regulation in Vascularized Composite Tissue Transplantation". MGH, a...
- This federal Project Grant award, valued at $453,750.00 and effective September 1, 2025, was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports a research program led by The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to advance the understanding of perioperative neurocognitive disorders (PND) and their association with disruptions in...
- The Department of the Army Medical Command, through the Military Medical Research and Development (CFDA 12.420) federal grant program, awarded a $1,498,368 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), with a performance period from August 1, 2024 to July 31, 2027. The grant supports research to elucidate the molecular mechanisms of tumor-immune dynamics and evolution in response to radiation, in order to optimize treatment of high-...
- The federal Project Grant award of $999,806.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research at The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to study innate lymphoid cells as new targets to reduce vascularized composite tissue transplant rejection. The award, which runs from September 30, 2024 to September 29, 2027, will enable MGH to conduct innovative biomedical research,...
- This federal Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) program provides $320,000.00 in funding to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on "GAMMA DELTA T CELL LIGANDS IN MS". The award period runs from November 1, 2024 to October 31, 2026. As a major recipient of federal research funding, MGH will leverage its extensive...
The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), received a $1,485,000 Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The award period runs from September 1, 2025 to August 31, 2028. The grant supports research focused on the discovery and characterization of programmable biological systems, particularly new RNA-guided functions found in bacterial defense mechanisms like CRISPR-Cas systems. The research aims to uncover novel programmable proteins and enzymes that could enable new capabilities to interrogate, alter, and control cellular functions based on genetic information. This work builds on previous breakthroughs in genome editing technology enabled by the discovery of CRISPR-Cas9. The research is expected to transform biology and provide critical molecular tools to study the human genome.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 8/25/25 |