Project Grant DP2HL185099
- The National Science Foundation awarded a $500,000 Project Grant to the University of Washington under the Biological Sciences federal grant program (CFDA 47.074) to investigate olfactory learning and neuromodulation in the Aedes aegypti mosquito from June 1, 2023 to May 31, 2026. The research aims to understand how odor learning modifies mosquitoes' biting behaviors through three objectives: testing whether mosquitoes only learn certain odors corresponding to antennal lobe glomeruli tuning;...
- The University of Washington received a $458,849 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct research aimed at uncovering the sensory mechanisms mosquitoes use to detect blood. The project seeks to leverage emerging single-cell RNA sequencing and high-throughput genetic analysis approaches to deeply characterize the diversity of sensory neurons in the mosquito labrum (feeding structure) and...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $707,696 to The Johns Hopkins University from November 2024 through October 2029. The funding supports research to identify volatile organic compounds in human scent signatures that modulate attractiveness to the African malaria mosquito Anopheles gambiae, a key disease vector. The research aims to characterize...
- This Project Grant from the National Institutes of Health's National Institute on Deafness and Other Communication Disorders, under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $405,048.70 in funding to Rockefeller University. The grant supports research to elucidate the structural determinants of odor specificity in insect olfactory receptors in order to gain fundamental insights into sensory processing of olfactory information in insects....
- This Project Grant award of $506,842.00, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA Program 93.173 "Research Related to Deafness and Communication Disorders", aims to identify powerful mosquito repellents that target their olfactory and gustatory systems. The research will validate computationally-predicted repellents and pyrethroid analogs, and test combinations for effectiveness in reducing contact between humans and...
- This federal Project Grant award for $329,039, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to determine the genetic relatedness, effective population size, and local adaptation of invasive Aedes aegypti mosquito populations. The award aims to advance understanding of how evolutionary forces shape the dispersal and population dynamics of this mosquito species, which can transmit...
- The University of California, San Diego (UCSD) was awarded a $500,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences (CFDA 47.074) federal grant program. Through this three-year award beginning June 1, 2023, UCSD will investigate olfactory learning and neuromodulation in the Aedes aegypti mosquito vector. The research aims to elucidate the role of dopamine-mediated plasticity in early olfactory circuits and how...
- This Project Grant award from the National Science Foundation (CFDA 47.049 - Mathematical and Physical Sciences) will develop an early-warning system to forecast surges in disease-carrying mosquito populations in the United States. The $300,000 award, effective September 1, 2025 through August 31, 2028, will create modeling tools and ensembling approaches to generate 1- to 4-week ahead forecasts of the relative abundance of Aedes aegypti and Aedes albopictus mosquitoes. The forecasts will be...
- This Project Grant award of $651,084, made by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports research to determine how microbes influence the response of their mosquito host to climate change, with a focus on the impacts on Hawaiian honeycreepers, an endangered bird species. The research aims to: Clarify the landscape-scale population dynamics of the mosquito vector Culex quinquefasciatus and its microbiome across an elevational gradient in Hawaii....
- The Project Grant award of $449,625.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program aims to develop a novel mouse model of arthropod-borne virus (ABV) transmission. The model will co-engraft a functional human immune system and human skin organoids to better understand the human cutaneous responses to ABV transmission, which is critical for developing effective antiviral countermeasures. This...
This Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $1,471,500.00 to the Trustees of Boston University to conduct research on how mosquitoes detect and respond to human odor. The primary objectives are to: 1) identify the neurons in the mosquito brain that encode human odor, 2) determine how olfactory information converges to guide human host-seeking behavior, and 3) identify the circuit mechanisms that combine information about odor and carbon dioxide to drive mosquito host location. The award period runs from September 1, 2025 to August 31, 2028. The findings from this research are expected to advance the scientific understanding of mosquito olfaction and provide insights that could inform the development of new strategies to disrupt mosquito-human interactions and reduce the transmission of mosquito-borne diseases.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.5m | 8/26/25 |