Project Grant DP2AI192443
- The National Science Foundation awarded a $500,000 Project Grant to the University of Washington under the Biological Sciences federal grant program (CFDA 47.074) to investigate olfactory learning and neuromodulation in the Aedes aegypti mosquito from June 1, 2023 to May 31, 2026. The research aims to understand how odor learning modifies mosquitoes' biting behaviors through three objectives: testing whether mosquitoes only learn certain odors corresponding to antennal lobe glomeruli tuning;...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $648,924 Project Grant to Iowa State University of Science and Technology under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The project, titled "Mosquito Extracellular Vesicles in Malaria Parasite Killing and Immune Priming," aims to obtain a mechanistic understanding of the role of mosquito extracellular vesicles in the mosquito immune system's recognition and killing of...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $707,696 to The Johns Hopkins University from November 2024 through October 2029. The funding supports research to identify volatile organic compounds in human scent signatures that modulate attractiveness to the African malaria mosquito Anopheles gambiae, a key disease vector. The research aims to characterize...
- This federal Project Grant award of $429,000.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The objective of this 2-year project is to: 1) Map chromatin architecture during immune activation in mosquito hemocytes, and 2) Identify gene regulatory networks for the immune deficiency (IMD) pathway genes by modulating enhancer RNA (eRNA) function. The project aims to enhance the...
- This Project Grant award from the Department of Health and Human Services National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $1,471,500.00 to the Trustees of Boston University to conduct research on how mosquitoes detect and respond to human odor. The primary objectives are to: 1) identify the neurons in the mosquito brain that encode human odor, 2) determine how olfactory information converges to guide human host-seeking behavior, and 3)...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $423,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Texas A&M University System Health Science Center. The grant, awarded on July 17, 2025, aims to develop an intein-based QF2 system for controllable protein expression in the nervous system of the Aedes aegypti mosquito. This research seeks to leverage genetic and synthetic biology tools to disrupt the propagation of...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), is funding research to develop new tools and technologies for vector control of the Aedes aegypti mosquito, an important disease vector. The key focus is on evaluating conditional and sex-specific lethal systems that can restrict lethal transgene expression and reduce the fitness load on mosquito populations, as...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $135,107 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Florida on June 20, 2025. The grant supports the development of a novel methodology using X-ray micro-computed tomography (micro-CT) imaging to quantify mosquito blood-feeding rates, a key determinant of pathogen transmission for mosquito-borne diseases. The project aims to optimize protocols for sample...
- The federal Project Grant award of $512,581.00 was made by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award supports research at Iowa State University of Science and Technology to investigate the influence of prostaglandin E2 on cellular and humoral immunity in the mosquito Anopheles gambiae. The research aims to examine the mechanisms of prostaglandin E2-mediated immune function, immune priming,...
- This $157,884 Project Grant, awarded on December 26, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the effects of a chromosomal inversion in the Anopheles coluzzii mosquito on gene regulation and its relationship to malaria resistance. The central hypothesis is that genetic variation between the inversion forms leads to differential enhancer activity and gene...
The University of Washington received a $458,849 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct research aimed at uncovering the sensory mechanisms mosquitoes use to detect blood. The project seeks to leverage emerging single-cell RNA sequencing and high-throughput genetic analysis approaches to deeply characterize the diversity of sensory neurons in the mosquito labrum (feeding structure) and understand how they enable blood detection and feeding behaviors. The goal is to gain genetic access to different neuron classes to study their anatomical location, functional sensitivity, and behavioral impact, with the ultimate objective of identifying new strategies to control mosquito populations and mitigate the transmission of diseases like malaria, dengue, and Zika. The 5-year project is scheduled to run from August 1, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $458.8k | 7/30/25 |