Project Grant 2242604

Award Date 6/1/23
Completion Date 5/31/26
Dollars Obligated $500K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
La Jolla, CA 92093, USA
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The University of California, San Diego (UCSD) was awarded a $500,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences (CFDA 47.074) federal grant program.

Through this three-year award beginning June 1, 2023, UCSD will investigate olfactory learning and neuromodulation in the Aedes aegypti mosquito vector. The research aims to elucidate the role of dopamine-mediated plasticity in early olfactory circuits and how odor learning modifies mosquito biting behaviors. Specifically, UCSD researchers will test hypotheses about which odors mosquitoes can learn based on antennal lobe glomeruli tuning, and how coincident dopamine and odor input causes plasticity allowing mosquitoes to learn important olfactory stimuli.

Insights from this research have potential to inform new mosquito control strategies by advancing understanding of the neural bases of learning in these disease vectors. The award also supports training opportunities for students to prepare them for independent scientific careers in interdisciplinary insect neurobiology.

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