Project Grant DP2GM154015
Award Date
9/18/23
Completion Date
8/31/26
Dollars Obligated
$1.4M
Federal Agency
National Institute of General Medical Sciences
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02139, USA
Similar Awards
The Massachusetts Institute of Technology (MIT) was awarded a $800,000 Project Grant from the National Science Foundation (NSF) to conduct collaborative research titled "Learning How Mucus Shapes and Maintains Microbiomes" from September 1, 2021 through August 31, 2026.
Under the award, MIT researchers will work to advance understanding of the role that mucus plays in shaping and maintaining microbiomes. The research is funded through the NSF's Biological Sciences program (CFDA...
This $463,157 Project Grant award from the National Institute of General Medical Sciences (NIGMS) 93.859 Biomedical Research and Research Training program supports research to understand how self-organization in microbial populations, such as bacterial biofilms and gut microbiomes, impacts the evolution of antimicrobial resistance.
The principal investigators will conduct tightly-controlled experiments using the model pathogen Vibrio cholerae, tracking resistance evolution at cellular...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $371,333 Project Grant to the University of Denver to investigate the structure and functional roles of microbially-derived metallophores within human microbiomes. The 5-year grant, awarded on August 1, 2024, aims to elucidate how these metal-binding molecules modulate microbe-microbe interactions and their effects on microbial communities in the...
The National Institute of General Medical Sciences (NIGMS) awarded a $351,010 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the Massachusetts Institute of Technology (MIT) to support the development and characterization of cationic carbone-boracycles as far-red and near-infrared photoactive agents for potential applications in tumor diagnosis and treatment.
The key objectives of the 5-year project include: 1) synthesizing and functionalizing cationic boron...
This $647,301 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports research to advance the understanding of the mechanisms of iron-sulfur enzymes. The key objectives are to:
Synthesize and characterize chemical models of iron-sulfur enzyme intermediates to elucidate their electronic structures and reactivity patterns. This includes using synthetic chemistry to rationally alter the...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) aims to develop a novel approach combining modular fluorophores and super-resolution microscopy to investigate the structure, dynamics, and interactome of biomolecular condensates in bacteria. The $402,500 award to New York University (NYU), spanning Sep 2024 to Jul 2029, will enable the research team to apply this...
This $275,000 SBIR Phase I Project Grant, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a generalized process to formulate and stabilize beneficial microbes for widespread adoption. The project, conducted by Seia Bio Inc., seeks to address the challenge of microbial stability when exposed to stressors such as heat, UV light, shock, and humidity. The proposed R&D will advance the understanding...
The National Institute of General Medical Sciences (NIGMS) awarded a $402,500 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University to develop synthetic biology tools and strategies to engineer therapeutic and diagnostic (theragnostic) bacteria. The objective is to create bacterial systems that can sense specific disease cues, such as inflammation, infection, or metabolic disorders, and...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $396,510 to Brandeis University to conduct research on how archaea, a type of microbe, respond to mechanical stresses that mimic conditions in the human microbiome.
The research aims to advance the understanding of how microbiome complexity influences human physiology by studying the fundamental principles of how...
The National Institute of General Medical Sciences (NIGMS) awarded a $371,606 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Regents of the University of Michigan. The funding will support a research program to advance the understanding and design of RNA therapeutics and their delivery via nanomaterials. Key objectives include: (1) developing an ultrasensitive screening platform to identify RNA cargo and carrier determinants enabling functional in...