This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Wild Microbes Co aims to develop superior bacterial strains for the productive secretion of difficult-to-express proteins through precision fermentation. The project's broader impact is to create more cost-effective and environmentally sustainable methods for manufacturing proteins used in detergents, personal care products, and dairy. By engineering improved bacterial...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $294,388 supports the development of MedMicroMaps, a novel e-learning platform and immersive experience in the "microbial metaverse" for life science learners. The project aims to advance science education in microbiology through an interactive, virtual microbe world that makes complex scientific concepts more accessible, particularly for traditionally...
This Project Grant award from the National Science Foundation (NSF) under its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Tectaria Bio LLC to engineer cell lines with activated proteasomes for increased biomanufacturing efficiency. The project aims to test the feasibility and application of a novel technology to significantly increase the protein production capabilities of cell lines used in the manufacture of biologics, gene therapies, and vaccines....
This federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (CFDA 10.212 - Small Business Innovation Research (SBIR) Program / Small Business Technology Transfer (STTR) Program) provides $175,000 to Seia Bio Inc. to develop a proprietary coating technology that protects beneficial probiotic microbes, such as Faecalibacterium, from environmental stressors. This will enable the expanded use of these microbes as alternatives to antibiotics...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Revivbio, Inc., a minority-owned and woman-owned small business in Cambridge, MA, aims to develop an enzymatic bioremediation strategy to degrade per- and polyfluoroalkyl carboxylic acids (PFCAs), a class of toxic and bioaccumulating per- and polyfluoroalkyl substances (PFAS). The project will leverage cutting-edge protein engineering techniques, including generative...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to 37Degrees, Inc. aims to develop a portable and modular system for long-term live cell and tissue culture imaging. The project objectives are to: 1) Enable a personal cellular video microscopy solution to democratize scientists' ability to visualize dynamic biological phenomena over extended time periods, and 2) Overcome technical limitations in maintaining cell...
This $305,000 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a novel technology that enhances plant mitochondrial function using light to improve crop growth and stress tolerance. The project, led by Luminova Biotech LLC, aims to demonstrate proof-of-concept for introducing this technology into model plant systems, with the goal of increasing productivity and resilience across a...
The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Delaqua Pharmaceuticals, Inc. aims to enhance the therapeutic use of hydrophobic drugs through a polymeric micelle approach to drug solubilization. The key objectives are to 1) improve the formulation of spherical micelles for enhanced stability and drug solubilization, 2) perform initial toxicity studies to establish the safety of the platform, and 3) demonstrate...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,431,000 Project Grant to the Massachusetts Institute of Technology (MIT) to develop self-assembling nanomaterials that can protect microbes from processing, transportation, and storage stresses. The goal is to enable the production of important but challenging microbial therapeutics that are difficult to manufacture. The 3-year project, with an award date of September 18, 2023, aims to elucidate the mechanism by which...