This Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) supports research to determine whether micro-stimulation of neurons in the visual cortex can generate perceptions of 3D object shape. The $232,500 award to The Johns Hopkins University will combine electrophysiology, stimulation, and behavioral experiments in macaque monkeys to test the hypothesis that activating neurons in the V4 region encoding 3D geometric shape fragments can bias visual perception. The...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, will fund the development of a new "mesoscopic electrophysiology" recording system to study brain function in non-human primates. The $606,548 award aims to create two fully functional mesoscopic electrophysiology systems, which will combine the large field of view...
The University of Pittsburgh received a $215,896 Cooperative Agreement award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award, titled "N3-PREP (NEUROLOGY, NEUROSURGERY, & NEUROPATHOLOGY PITT RESEARCH EDUCATION PROGRAM)", will support the training of physician-neuroscientists to translate neuroscience discoveries into...
This $1,383,800 federal Project Grant award from the Department of Health and Human Services' National Institutes of Health, under the Trans-NIH Research Support (CFDA 93.310) program, supports the University of Pittsburgh's research to develop new methods for creating and testing developmental signaling patterns. The project aims to leverage high-throughput optogenetic manipulation to build libraries of paired data on developmental signaling patterns and resulting tissue structures. This...
The University of Pittsburgh received a $492,749 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The goal of this 5-year research project is to develop a non-invasive magnetic resonance imaging (MRI) technique with high pH sensitivity to predict tissue fate and evaluate the risk of reperfusion injury in acute ischemic stroke...
The University of Pittsburgh received a $574,427 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award, with a project period from September 20, 2024 to August 31, 2029, will fund research focused on understanding how altered amino acid metabolism in glioblastoma, an aggressive brain cancer, can promote tumor growth and suppress...
The National Eye Institute (NEI) awarded a $606,025 Project Grant (CFDA 93.867 - Vision Research) to William Marsh Rice University to establish the feasibility and acquire key knowledge to build a lasting lateral geniculate nucleus (LGN) visual prosthesis with unprecedented visual coverage. The project aims to interface large-scale, ultraflexible electrodes with the LGN, the relay station between the retina and visual cortex, to elicit pattern perception and restore visual function for the...
This $392,119 Project Grant was awarded on September 1, 2024 by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to the University of Pittsburgh. The grant supports establishing statin/MBV-based therapies for enhancing optic nerve regeneration after traumatic optic neuropathy. The University of Pittsburgh, a major recipient of federal research grants, will leverage its academic expertise and research infrastructure to conduct this basic and...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $594,286.00 in funding to the University of Pittsburgh to conduct research on the functional logic of local circuits in auditory and parietal cortices. The research aims to compare the spatial and functional structure of excitatory impacts, inhibitory and disinhibitory...
This $300,000 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) supports research at the University of Pittsburgh to develop new analytical tools for understanding information flow and selective attention in large-scale brain networks. The 5-year project aims to integrate existing datasets of neural activity and anatomical connectivity to provide a mechanistic understanding of communications between...