Project Grant DESC0015188

This $295,308 Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will support the development and validation of a novel class of scanning probe microscopy (SPM) probes for rapid identification of infectious disease agents. The awardee, Actoprobe LLC, aims to dramatically improve the sensitivity and spatial resolution of scanning...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $952,862 to the University of Rochester to develop flexible, multi-wavelength fiber optic light sources for advanced nonlinear and multimodal imaging. The key objectives are to: (1) create diode-laser driven fiber time-lens picosecond sources with fiber parametric amplification for flexible, multi-wavelength picosecond...

This $388,983 federal Project Grant award from the National Science Foundation (NSF) Division of Chemistry's Chemical Measurement & Imaging Program and Chemistry of Life Processes Program supports the development of a new optical microscope by Professor Eric Potma at the University of California, Irvine. The instrument leverages chiral sum-frequency generation (SFG) microscopy to visualize protein structures in cells and tissues without the need for chemical labeling. This label-free imaging...

This Project Grant from the National Science Foundation's Office of Integrative Activities, under the Integrative Activities program (CFDA 47.083), provides $468,564 to support the acquisition of a next-generation Near-field Scanning Optical Microscope (NeaSNom) at the University of Central Florida. The instrument, custom-built by NeaSpec, will enable simultaneous Atomic Force Microscopy and nanoscale (10 nm spatial resolution) Fourier Transform Infrared and Tip-Enhanced Raman Spectroscopy. It...

This $546,494 award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) will enable the University of California, Irvine (UCI) to acquire a high-resolution optical photothermal infrared (OPTIR) microscope system. This new microscope will support cutting-edge scientific research programs at UCI, foster collaborations with California State University Fullerton, and accelerate partnerships with industry. The OPTIR microscope will allow for sensitive,...

The National Science Foundation Division of Chemistry awarded Columbia University a $442,564 Project Grant under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop new microscopy techniques for imaging ultrafast chemical transformations between molecules separated by large distances. Principal Investigator Milan Delor and his research group will leverage polaritons, which are part-light part-matter particles, to significantly increase the sensitivity of optical...

This Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) provides $1,386,474 to Baylor College of Medicine to acquire a Femtonics ATLAS microscope. The ATLAS microscope enables rapid, high-resolution 3D imaging of neuronal activity using advanced fluorescence techniques like calcium, voltage, and neurotransmitter reporters. This cutting-edge imaging system will support a diverse portfolio of NIH-funded neuroscience research...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Nanores LLC aims to develop a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues with nanoscale precision. The key products to be delivered include: An advanced fluorescence imaging system incorporating adaptive optics and spinning disk technology to enable 3D imaging of biological samples up...

This $573,147 National Science Foundation Project Grant through the Integrative Activities program (CFDA 47.083) will fund the acquisition of a Zeiss LSM 900 confocal microscope with Airyscan for Queens College of the City University of New York's Core Facility for Imaging, Cell, and Molecular Biology. The microscope will enhance multidisciplinary research and training at the minority-serving institution by enabling new microscopy courses and outreach activities promoting STEM access for...

The National Institute of General Medical Sciences (NIGMS) awarded Trestle Optics LLC a $305,647 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to develop a novel photothermal microscopy system for non-destructive, high-resolution screening and sorting of microalgae to identify and enrich strains producing high-value polyunsaturated fatty acids. The project aims to engineer and prototype a microfluidic platform integrating photothermal imaging...