This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Nanores LLC aims to develop a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues with nanoscale precision. The research objectives include optimizing the system for imaging up to 250 micrometers in depth with a resolution of 10-20 nanometers, and demonstrating its ability to simultaneously image multiple molecular targets. This innovation has the potential to revolutionize biomedical research by enabling advanced fluorescence imaging of biological tissues at unprecedented depth and resolution, with applications in drug discovery, disease diagnostics, basic biology, and biological education. Subawards are planned under this grant.
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