The National Institute of General Medical Sciences (NIGMS) awarded a $1,048,299 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to The Research Foundation for the State University of New York (RF-SUNY) on August 1, 2025. The funding will support the acquisition of a LUMICKS C-TRAP correlative force and fluorescence optical tweezer system, which will enable real-time observation, monitoring, and quantitation of interactions between...
The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded Rockefeller University a $934,875 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286). The grant, effective September 1, 2024 through May 31, 2027, will fund the development of two fiber-based amplifier and detection systems (F-BADS) to enhance laser scanning microscopy (LSM) techniques, including optical coherence tomography (OCT),...
This $390,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) will support the development of a multiparametric fluorescence microscopy framework to correlate metabolic changes with cellular manipulations and physical/biophysical properties. The award, granted to Georgetown University, will establish a seamless workflow to quantify and correlate fundamental cellular interactions, such as...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $374,399 in funding to the University of California, Davis to develop innovative two-photon microscopy systems with scattering correction capabilities for deep tissue imaging. The goal of this research is to enable high-speed, high-resolution imaging through scattering biological tissues, such as intact mouse organs, by...
The National Institute of General Medical Sciences (NIGMS) awarded a $291,224 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of Chicago to develop BRAVE-EM, a novel imaging technique that combines the wavelength specificity of optical light microscopy with the spatial resolution and volume imaging capabilities of electron microscopy. This 5-year research program, starting on August 15, 2024, seeks to enable simultaneous functional and structural imaging...
The National Institute of General Medical Sciences (NIGMS) awarded a $719,606 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Clarkson University. The grant, which runs from Sep 17, 2024 to Jun 30, 2029, aims to advance the visualization and quantification of subcellular and biomolecular mechanics through innovative mechanochemical protocols. The key products and services to be delivered include: 1) Pioneering a comprehensive library of molecular...
The National Institute of General Medical Sciences (NIGMS) awarded a $330,076 Project Grant to Trestle Optics LLC under the Biomedical Research and Research Training (CFDA 93.859) federal grant program. The grant funding will support the development of a photothermal microscopy platform that can non-destructively profile metabolites in individual cells. The project aims to integrate photothermal microscopy with spatial light interference imaging to create a system capable of real-time,...
The National Institute of General Medical Sciences (NIGMS) awarded a $607,164 Project Grant under CFDA 93.859 (Biomedical Research and Research Training) to Health Research, Inc.'s Wadsworth Center Division located in Menands, NY. The grant, effective September 30, 2024 through July 31, 2027, aims to develop a novel polymer-based cell culture substrate and associated protocols to enable correlative light and electron microscopy (CLEM) studies of functional cells cultured on permeable/porous...
The National Institute of General Medical Sciences (NIGMS) awarded a $290,536 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to Trestle Optics LLC, a small disadvantaged business, to develop a novel high numerical aperture catadioptric lens for ultra-broadband multimodal microscopy. This lens will enable advancements in existing nonlinear optical imaging modalities, such as three-photon excited fluorescence and third-harmonic generation, by overcoming limitations of...
This $402,500 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) aims to develop a novel approach that combines modular fluorophores and correlative super-resolution microscopy to investigate the structure, dynamics, and interactome of biomolecular condensates in bacteria. The project, being conducted at New York University, will apply this "opto-proteomic toolbox" to understand the role of...