Project Grant 2616041
- The National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation awarded Michigan State University $370,721 on September 1, 2026, under the Engineering grant program (CFDA 47.041) to develop an integrated experimental and computational framework characterizing coronary blood vessel mechanics and their interaction with heart muscle tissue. The research establishes a multiscale model coupling coronary blood flow with cardiac mechanics, incorporating vascular impedance...
- Federal Project Grant Award Summary San Diego State University Research Foundation received $115,117 in federal funding from the National Science Foundation's (NSF) Directorate for Engineering (CFDA 47.041) under a collaborative research project grant awarded August 15, 2025, with completion targeted for June 30, 2026. The award supports fundamental bioengineering research investigating changes in right ventricle viscoelasticity under acute stress and chronic pulmonary hypertension. The research...
- The University of California, San Diego was awarded a $551,341 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) for the period of March 1, 2021 through February 28, 2026. The grant funds research into the mechanical and structural adaptations of blood vessels in pulmonary arterial hypertension. Specifically, the university will examine how blood vessels in the lungs change over time in response to high blood pressure conditions. This work will further the...
- The National Science Foundation (NSF) has awarded a $266,856 Project Grant to the San Diego State University Research Foundation under the NSF Engineering program (CFDA 47.041) for the period of May 1, 2024 to April 30, 2027. The grant aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation dynamics to understand how microbubble clusters can be used to navigate through blood vessels. The research team will...
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded the University of Maryland Baltimore County $471,305 on September 15, 2026, under the Engineering program (CFDA 47.041) to develop a microfluidic model and metabolomic analysis framework investigating why diabetic patients face elevated cardiovascular disease risk despite controlled blood glucose levels. The project will construct a laboratory model using real human artery tissues...
- This National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) project grant award provides $598,884 over 4 years to The Regents of the University of California, doing business as the University of California, Berkeley, to develop a novel suite of simulation tools for modeling vascular biomechanics and mechanobiology as part of the open-source SimVascular software platform (CFDA No. 47.041 Engineering). The project aims to enhance...
- The National Science Foundation awarded a $279,606 Project Grant to the University of California Irvine under the Engineering federal grant program (CFDA 47.041). The grant supports collaborative research to develop multiscale computational models characterizing how heart muscle cells adapt mechanically to changes in load conditions. Through experimental measurement and multi-scale modeling, the university researchers will elucidate the acute functional response and long-term remodeling response...
- The National Science Foundation awarded a $542,441 Project Grant to the Texas A&M Engineering Experiment Station to develop a validated hybrid echocardiography-computational fluid dynamics framework for patient-specific cardiac assessment under the Engineering (47.041) federal grant program. The project aims to create a computational pipeline using standard echocardiography scans to model cardiac flow and function, and compute in vivo mechanical and electrophysiological properties for...
- This National Science Foundation (NSF) Project Grant award, under the Engineering program (CFDA 47.041), provides $279,376 to Washington University to conduct research on the mechanisms of right ventricular (RV) stiffening and its impact on cardiac health. The project aims to delineate and model the intra- and extra-cellular mechanisms contributing to RV myocardial stiffening using a combination of experimental and computational approaches. Specifically, the researchers will perform...
- The National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation awarded Iowa State University $500,000 on August 1, 2026, under the Engineering program (CFDA 47.041) to develop multiscale computational models of vein graft failure in coronary bypass surgery. The project integrates computer modeling of blood flow and vascular remodeling to understand the mechanisms driving vein graft failure, which occurs at unacceptably high rates following coronary artery bypass...
The National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation awarded San Diego State University Foundation $215,001 on September 1, 2026, to develop an integrated experimental and computational framework characterizing coronary blood vessel mechanics and their interaction with cardiac muscle under healthy and diseased conditions. The research will establish a multiscale model coupling coronary blood flow with cardiac mechanics, incorporating vascular impedance analysis and wave intensity analysis. Experimental measurements from healthy animal models will validate the computational framework, which will then quantify how reduced blood supply alters vascular wave propagation, pressure transmission, pulse wave energy, and mechanical interactions between coronary vessels and the myocardium. The project will generate computational tools applicable to blood flow analysis in other organs, integrate findings into biomechanics education, and engage K-12 students and the public on cardiovascular health and biomedical engineering awareness. The award funds work performed in San Diego, California, with a period of performance from September 1, 2026, through August 31, 2029. This is a Project Grant under the NSF Engineering program (CFDA 47.041).
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $215.0k | 7/20/26 |