Project Grant 2543650
- Federal Grant Award Summary Iowa State University of Science and Technology received a $999,745 Project Grant from the National Science Foundation's Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049) awarded September 15, 2025, with completion targeted for August 31, 2028. The award funds development of a multiscale digital twin framework—termed VASCTWIN—designed to predict and control blood vessel growth following cardiac injury by integrating...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $450,000 project grant from the National Science Foundation's Engineering program (CFDA 47.041) awarded June 1, 2025, with completion scheduled for May 31, 2028. The award funds development of In Vitro Biomanufacturing on a Chip (IBOC), an advanced microfluidic platform designed to accelerate bioproduct development and commercialization. The IBOC system integrates nanophotonic sensors—specifically a...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $319,574 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded April 15, 2025, with completion targeted for March 31, 2028. The award funds fundamental research to develop a swelling-porous media model that characterizes interstitial fluid dynamics in brain tissue,...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $515,000 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Electrical, Communications and Cyber Systems under the Engineering program (CFDA 47.041), effective September 1, 2025, through August 31, 2030. The project will develop principled methods and algorithms for multi-task representation learning in bandit and reinforcement learning settings, with...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $552,957 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041), effective October 15, 2025, with a completion date of September 30, 2028. The award funds the development of a chip-based in vitro platform designed to study interactions between gut microbiota and brain tissue models through an artificial blood-brain barrier (BBB). This reductionist research model will...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $550,000 Faculty Early Career Development (CAREER) award from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation (CFDA 47.041—Engineering program) effective August 1, 2026, through July 31, 2031. The award supports fundamental research to advance the printability and industrial deployment of aluminum alloys through laser powder blown directed energy deposition...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $1.18 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through August 31, 2029. The award funds development of a Scientific Machine Learning (SciML)-accelerated cardiovascular digital twin platform designed to personalize long-term heart valve interventions for valvular heart...
- Federal Grant Award Summary Iowa State University of Science and Technology received a $182,558 Project Grant from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), awarded May 6, 2026 with completion targeted for February 28, 2029. The research project will develop a bioinspired drug discovery strategy leveraging the foreign body response (FBR) within...
- Federal Project Grant Award Summary Iowa State University of Science and Technology received a $320,525 CAREER grant award from the National Science Foundation (NSF) Division of Information and Intelligent Systems under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070), effective August 1, 2025, through July 31, 2030. This project grant supports the development of novel conformal inference models and algorithms designed to enable reliable uncertainty-aware...
- Federal Grant Award Summary North Carolina State University received a $600,000 Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation (CFDA 47.041 - Engineering program) effective October 1, 2025, through September 30, 2028. This BRITE Relaunch initiative delivers fundamental research data and computational models characterizing the biomechanics and mechanobiology of venous valve degeneration in chronic venous insufficiency. Primary...
Iowa State University of Science and Technology received a $500,000 Faculty Early Career Development (CAREER) award from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041), effective August 1, 2026 through July 31, 2031. The primary deliverable is a unified multiscale computational modeling framework designed to elucidate the mechanisms of vein graft failure in coronary bypass surgery. The research outputs will include physics-based computer models that simulate blood flow dynamics and vascular adaptation across multiple biological scales, enabling researchers to understand how hemodynamic loads, inflammation, and surgical trauma interact to determine graft outcomes. In addition to the computational modeling tools, the award supports the development of a virtual testing framework for evaluating biotechnologies and therapeutic interventions aimed at improving vein graft performance. The project incorporates an educational component that delivers training in multiscale computational modeling techniques, develops new educational modules for biomedical engineering curricula, and extends the modeling approaches to address other blood vessel-related diseases. All research and educational activities will be performed at Iowa State University's facilities in Ames, Iowa.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $500.0k | 4/30/26 |