Project Grant 2610176
- Federal Project Grant Award Summary Case Western Reserve University received a $695,000 CAREER award from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041, Engineering program) on July 1, 2025, with a completion date of June 30, 2030. The project delivers fundamental research into the structural properties and intracellular behavior of DNA origami nanoparticles—synthetic deoxyribonucleic acid (DNA) nanostructures...
- Project Grant Award Summary Case Western Reserve University received a $554,921 Project Grant award from the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049), effective September 1, 2025, through August 31, 2028. Under the direction of Dr. Genevieve Sauve, this research project develops innovative chemical strategies to enhance the mechanical properties and electrical performance of semiconducting conjugated polymers...
- Federal Grant Award Summary Case Western Reserve University received a $1,014,796 Project Grant award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, through August 31, 2028. The award funds fundamental research to identify and characterize the molecular interactions required for targeting defective messenger RNA (mRNA) to nonsense-mediated decay (NMD), a critical cellular...
- This $1,500,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program will support research at Northwestern University to develop innovative protein-based biomaterials. The research aims to (1) engineer mussel foot proteins with superior underwater adhesive properties compared to wild-type sequences, and (2) create resilin-inspired bioelastomers with high strength while retaining natural mechanical resilience. The proposed...
- This $510,000 federal Project Grant was awarded on May 1, 2025 by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program. The grant was awarded to Case Western Reserve University to support research aimed at "Enhancing Piezoelectricity in Semicrystalline Ferroelectric Polymers via Electrostriction of the Oriented Amorphous Fraction." The research will employ computer simulation, advanced polymer processing, structural analysis, and...
- Federal Project Grant Award Summary The National Science Foundation (NSF), Division of Materials Research, awarded a collaborative research project grant of $489,891 to The Trustees of Princeton University (awarded July 1, 2026; completion date June 30, 2029) under CFDA 47.049 (Mathematical and Physical Sciences). This project investigates the mesoscopic properties and complex morphologies of multiphase biomolecular liquids inspired by phase-separated condensates observed in living cells....
- Case Western Reserve University was awarded a $640,000 Project Grant from the National Science Foundation on May 1, 2021 to support research titled "UNDERSTANDING THE MOBILE ORIENTED AMORPHOUS FRACTION IN SEMICRYSTALLINE FERROELECTRIC POLYMERS AND ITS UNIQUE CONTRIBUTION TO ELECTROSTRICTION." The award is being administered under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which supports advancing scientific knowledge and understanding of major problems...
- This $358,040 Project Grant, awarded by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049), supports fundamental computational research conducted by Professor Mesfin Tsige at the University of Akron from September 1, 2025, through August 31, 2028. The primary deliverable is advanced theoretical and computational understanding of macroion self-assembly and solvation behavior through a multi-scale modeling approach. The...
- This $200,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research effort led by New York University (NYU) School of Medicine. The project aims to enhance the design of fluorinated protein fibers and hydrogels for medical applications. Key objectives include: 1) generating coiled-coil fluorinated fibers for controlled drug delivery, 2) developing temperature-responsive fluorinated hydrogels,...
- This $500,000 federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) supports research at Northwestern University to develop de novo designed proteins as mechano-responsive junctions in protein-polymer networks. The key objectives are to: (i) synthesize and computationally simulate de novo designed proteins and their respective protein-polymer networks, and (ii) develop techniques for mechanical characterization...
This $427,913 Project Grant, awarded July 15, 2026, by the National Science Foundation (NSF) Division of Materials Research under the Mathematical and Physical Sciences program (CFDA 47.049), supports fundamental research into biomacromolecular phase separation and assembly within elastic environments. Case Western Reserve University will conduct a three-year research initiative (completion June 30, 2029) to develop predictive understanding of how local elasticity and anisotropy regulate the behavior and organization of biological molecules in crowded, water-filled matrices. The research will produce simplified experimental systems that manipulate material stiffness, salt concentration, and network structure at the molecular scale to control protein assembly and ordering mechanisms, with the ultimate objective of enabling 3D-printable, self-organizing biomaterials with responsive properties. The project will advance biotechnology applications including responsive drug-delivery systems, biosensors, engineered extracellular-matrix scaffolds, and tissue engineering solutions. Additionally, the research team will strengthen the Northeast Ohio biotechnology workforce through undergraduate and graduate student training and technology transfer partnerships with regional manufacturing and innovation organizations, thereby translating fundamental research findings toward commercialization and practical application in the biomedical and materials science sectors.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $427.9k | 7/1/26 |