Project Grant 2323316

Award Date 10/1/23
Completion Date 9/30/27
Dollars Obligated $500K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Evanston, IL 60208, USA
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This $500,000 federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) supports research at Northwestern University to develop de novo designed proteins as mechano-responsive junctions in protein-polymer networks.

The key objectives are to: (i) synthesize and computationally simulate de novo designed proteins and their respective protein-polymer networks, and (ii) develop techniques for mechanical characterization of these networks at the microscale to accelerate the discovery and deployment of proteins as junctions in biohybrid and engineering bioplastic materials. The research aims to create superior protein-based thermosets that can be processed via additive manufacturing, with a focus on understanding how protein unfolding and refolding within the network topology impacts the mechanical properties. This work addresses national needs for more sustainable manufacturing methods and advanced materials development.

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