Project Grant 2542305
- Federal Project Grant Award Summary The University of Chicago received a $501,879 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) for the period September 1, 2025 through August 31, 2028. This collaborative research project delivers fundamental scientific knowledge regarding bacterial gliding motility mechanisms through an integrated multidisciplinary approach combining genetics, biophysics,...
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- Federal Grant Award Summary The University of Illinois received a $396,500 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through June 30, 2030. This award funds fundamental biomedical research focused on probing and controlling chirality across multiple biological scales using nanophotonic platforms. The research project will develop cutting-edge nanophotonic...
- Federal Grant Award Summary The University of Chicago received a $300,000 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective October 1, 2025, through September 30, 2027. The award funds research to develop a novel class of dynamic molecules based on intrinsically disordered proteins (IDPs) that can sense environmental cues and trigger rapid, gated cellular...
- Federal Project Grant Award Summary The University of Chicago received a $820,000 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025, through April 30, 2030. This award funds a research initiative to investigate bacterial secretion systems using cryo-electron tomography (cryo-ET) and associated advanced microscopy methodologies. The project will deliver fundamental structural...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $835,085 to Reed Institute under the Biological Sciences program (CFDA 47.074) on June 1, 2026, for a five-year CAREER project titled "Comprehensive Investigation of the Molecular Mechanisms of Bacterial Manganese Homeostasis." The project will deliver fundamental research outputs including detailed molecular structures of bacterial manganese transport and regulatory...
- Federal Grant Award Summary Loyola University of Chicago received a $775,664 Project Grant from the National Science Foundation's Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), effective June 1, 2026 through May 31, 2031. This CAREER award funds fundamental research investigating how bacterial populations evolve in response to elemental limitation, specifically examining changes in elemental composition and genetic adaptation when carbon, nitrogen, and...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Computing and Communication Foundations awarded $358,400 in project grant funding to the University of Illinois (Board of Trustees of the University of Illinois) under the Computer and Information Science and Engineering program (CFDA 47.070) for a collaborative research initiative spanning October 1, 2025, through September 30, 2028. This project develops an information-theoretic framework and computational algorithms...
- Federal Project Grant Award Summary The University of Illinois received a $600,000 Project Grant award effective October 1, 2025, through September 30, 2028, from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041). This BRITE PIVOT research initiative delivers advanced engineering tools and methodologies that integrate spatial transcriptomics, multiplexed protein profiling, and mechanical characterization...
- Federal Project Grant Award Summary The University of Illinois received a $196,773 Project Grant award from the National Science Foundation's Division of Computing and Communication Foundations under the Computer and Information Science and Engineering program (CFDA 47.070), effective October 1, 2025, through November 30, 2026. This CAREER award supports fundamental research in graph algorithm design that exploits topological properties to accelerate computational tasks on network structures....
The University of Illinois received a $763,130 Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2026 through May 31, 2031. This CAREER award supports fundamental research to decode active and passive mechanisms driving bacterial chromosome dynamics in Escherichia coli. The research deliverables include a genome-scale atlas of chromosome motion, quantitative polymer-physics models explaining differential chromosomal region movement, high-resolution single-molecule tracking data, and super-resolution microscopy analysis integrating multiple experimental and computational approaches. The project combines advanced techniques including MINFLUX (Minimal Photon Fluxes) super-resolution microscopy, quantitative polymer-physics modeling, single-molecule tracking, and in vitro reconstitution experiments to characterize how biological processes and physical constraints shape chromosome behavior in living cells. In addition to research products, the award supports integrated education and outreach activities designed to strengthen quantitative approaches in biotechnology and build the biophysics workforce. Deliverables include training programs in quantitative biophysics across multiple educational levels, expanded research experiences for undergraduates, dissemination of experimental protocols and analysis tools to the broader scientific community, and educational content highlighting physicists' contributions to biology and medicine. This project addresses a critical gap in understanding chromosome function by moving beyond static genome sequencing and imaging to characterize dynamic chromosomal behavior, with outcomes intended to inform future efforts to predict and engineer genome function.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $763.1k | 5/14/26 |