Project Grant 2540645
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded the University of Washington a $836,598 Project Grant (CFDA 47.074, Biological Sciences) effective September 1, 2025, through August 31, 2030. This CAREER award funds research to develop tools and methodologies for reading and sequencing expanded genetic alphabets (XNA) containing synthetic nucleotide bases beyond the standard adenine, thymine, guanine, and cytosine. The...
- Federal Project Grant Award Summary Emory University's Office of Sponsored Programs received a $1,103,118 CAREER (Faculty Early Career Development) Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), awarded September 15, 2026, with completion targeted for August 31, 2031. The award supports fundamental research elucidating the molecular mechanisms of pointed-end actin polymerization mediated...
- Federal Grant Award Summary Auburn University received a $1.55M CAREER Project Grant from the National Science Foundation's Division of Environmental Biology (Biological Sciences program, CFDA 47.074) effective July 1, 2026 through June 30, 2031. The award supports fundamental research comparing two closely related agricultural viruses—Tomato Spotted Wilt Virus (which infects a broad range of plant and insect hosts) and Soybean Vein Necrosis Virus (which exhibits limited host range)—to...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a CAREER grant totaling $1,004,780 to the University of North Carolina at Charlotte on July 1, 2026, with completion anticipated by June 30, 2031. This Project Grant under the Biological Sciences program (CFDA 47.074) supports fundamental research investigating how endofungal bacteria (bacteria living within fungal cells) communicate with and control their fungal hosts...
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- Federal Project Grant Award Summary The University of Massachusetts Medical School (UMMS) received a $1.1 million CAREER award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) to support fundamental research on novel bacterial immune systems for genome editing applications. Awarded August 1, 2025, with a completion date of July 31, 2030, this project will deliver scientific research outputs including...
- Federal Grant Award Summary Vanderbilt University received a $1,032,370 CAREER (Faculty Early-Career Development Program) Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), awarded August 1, 2026, with a completion date of July 31, 2031. This five-year award funds research investigating the dynamic interplay between DNA methylation and bacterial evolution, with the goal of advancing foundational...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $880,000 to the University of Massachusetts Lowell under the Biological Sciences program (CFDA 47.074) for a five-year CAREER grant (June 1, 2026 – May 31, 2031). The project investigates how transgenerational chromatin landscapes regulate cell fate and gene expression in Caenorhabditis elegans, focusing on the mechanisms of epigenetic inheritance—specifically, which histone...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Environmental Biology awarded $739,821 to the University of Florida under the Biological Sciences program (CFDA 47.074) for a five-year CAREER project commencing June 1, 2025, and concluding May 31, 2030. This Project Grant supports an integrated research and educational initiative investigating heterogeneity in lizard-malaria transmission through the combination of mathematical modeling and ecological experimentation....
- Federal Grant Award Summary Portland State University received a $1,020,345 Project Grant from the National Science Foundation's Division of Environmental Biology (CFDA 47.074 – Biological Sciences) effective September 1, 2026 through August 31, 2029. The grant funds research to advance understanding of crucivirus evolution and horizontal gene transfer between RNA and DNA viruses. The project will develop biotechnological and artificial intelligence (AI) tools to discover cruciviruses in...
Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded the University of Washington a $1.28M CAREER (Biological Sciences, CFDA 47.074) project grant effective July 1, 2026, through June 30, 2031. This research project investigates the genetic determinants controlling host range in Marseilleviridae giant viruses and their Acanthamoeba single-cell eukaryote hosts. The research will employ virological techniques to identify viral and host genes that determine susceptibility or resistance to giant virus infection, with deliverables including characterization of novel giant virus isolates, identification of resistant and susceptible Acanthamoeba strains, and molecular mechanisms underlying host-pathogen interactions. Findings are expected to contribute new biotechnologies, medical interventions, and fundamental scientific knowledge in viral immunology and host defense mechanisms. The award includes an integrated education component delivering a course-based research experience for undergraduate participants who will isolate and identify novel giant viruses and assess infection patterns across laboratory-adapted and environmental Acanthamoeba strains. This educational pathway provides students with practical training in environmental sampling, molecular biology techniques, and viral infection assays, strengthening the biotechnology workforce and aligning with NSF's biotechnology priorities. The project leverages Acanthamoeba as a robust model system for studying microbial eukaryote-virus interactions, building on preliminary observations of complex host-range variability within the Marseilleviridae family.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.3m | 6/25/26 |