Project Grant 2540620
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- Federal Project Grant Award Summary Florida State University received a $864,959 CAREER (Faculty Early Career Development) Project Grant from the National Science Foundation's Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), awarded July 1, 2026 through June 30, 2031. The award supports fundamental research investigating the causal relationships between epigenetic regulation, gene expression, and phenotypic diversity in Caenorhabditis elegans nematodes...
- Federal Project Grant Award Summary The University of Massachusetts Medical School (UMMS) received a $1.1 million CAREER award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) to support fundamental research on novel bacterial immune systems for genome editing applications. Awarded August 1, 2025, with a completion date of July 31, 2030, this project will deliver scientific research outputs including...
- Federal Grant Award Summary The National Science Foundation's Division of Molecular and Cellular Biosciences awarded a CAREER grant of $835,085 to Reed Institute (Reed College) on June 1, 2026, under the Biological Sciences program (CFDA 47.074). This five-year project, concluding May 31, 2031, will deliver fundamental research outputs investigating bacterial manganese homeostasis through structural and biochemical characterization of manganese influx and efflux proteins in Bacillus subtilis....
- Federal Grant Award Summary Vanderbilt University received a $997,860 Project Grant from the National Science Foundation's Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), awarded on August 15, 2025, with a completion date of July 31, 2029. The project investigates evolutionary adaptation and immune system regulation across different life stages, using the flour beetle Tribolium castaneum as a model organism. Primary deliverables include experimental...
- Federal Grant Award Summary The National Science Foundation's Division of Environmental Biology awarded the University of Arkansas a $1,079,060 CAREER grant (CFDA 47.074, Biological Sciences) effective July 1, 2026 through June 30, 2031 to investigate gene emergence and functional innovation through research on fish antifreeze proteins. The project will deliver research outputs including comparative genomic, transcriptomic, epigenomic, and phylogenetic analyses that elucidate how Type I...
- FEDERAL PROJECT GRANT AWARD SUMMARY Princeton University received a $1.0 million Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective August 1, 2025 through July 31, 2029. The award funds fundamental research on quorum sensing—a bacterial cell-to-cell communication process that enables bacterial populations to synchronize behavior based on population density and species...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded the University of Washington a $836,598 Project Grant (CFDA 47.074, Biological Sciences) effective September 1, 2025, through August 31, 2030. This CAREER award funds research to develop tools and methodologies for reading and sequencing expanded genetic alphabets (XNA) containing synthetic nucleotide bases beyond the standard adenine, thymine, guanine, and cytosine. The...
- This $150,000 Project Grant awarded by the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program funds research at Vanderbilt University to elucidate the molecular mechanisms of DNA repair by a newly discovered bacterial enzyme. The project aims to understand how this enzyme protects microbes against toxic natural products, with the long-term goals of elucidating bacterial interstrand DNA crosslink repair pathways and discovering new genotoxic agents with...
- Federal Project Grant Award Summary This CAREER (Faculty Early-Career Development Program) award of $763,328 from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) supports research on dynamic protein design and engineering. The project, awarded June 15, 2026, and scheduled for completion May 31, 2031, is being conducted by the Research Foundation of The City University of New York (RFCUNY), operating as the...
Vanderbilt University's Division of Sponsored Programs Administration received a $1,032,370 Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074) effective August 1, 2026, through July 31, 2031. This CAREER award supports fundamental research investigating the dynamic interplay between DNA methylation and bacterial evolution. The project will deliver cutting-edge research outputs including identification of methylation targets in bacterial genomes using advanced DNA sequencing technologies, machine learning algorithms, and high-performance computing. The research will advance foundational knowledge of genome evolution and bacterial adaptation to environmental challenges while developing novel experimental and computational approaches for studying genome structure and evolution in microorganisms. In addition to research deliverables, the award integrates educational outcomes through engagement of undergraduate students in discovery-driven learning at the intersection of microbiology, genomics, and data science. This educational component supports workforce development in bioinformatics and biotechnology fields, contributing to the NSF's broader mission of strengthening the nation's scientific enterprise. The five-year project addresses a significant gap in understanding the evolutionary significance of epigenetic modifications in bacterial genomes, a previously poorly characterized area with potential implications for gene regulation and phenotypic plasticity.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 4/29/26 |