Project Grant 2528704
- Federal Project Grant Award Summary The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded $600,000 to the University of Illinois, effective September 1, 2025, through August 31, 2030. This CAREER award supports research focused on developing methods to optically reprogram and replicate neural circuits in zebrafish larvae as a model system for understanding and treating brain disorders. The core deliverable involves demonstrating signal transfer from healthy brains to...
- Federal Grant Award Summary The University of Illinois received a $597,232 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective August 1, 2025, through July 31, 2028. This award supports the development of intrinsic signal optoretinography (ISOR), a novel noninvasive imaging technique designed to detect early functional biomarkers of Alzheimer's disease in the retina....
- Federal Project Grant Award Summary The University of Illinois received a $600,000 Project Grant award effective October 1, 2025, through September 30, 2028, from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041). This BRITE PIVOT research initiative delivers advanced engineering tools and methodologies that integrate spatial transcriptomics, multiplexed protein profiling, and mechanical characterization...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded $407,216 to The Washington University in a Project Grant dated February 1, 2026, to develop a transcranial focused ultrasound system for targeted neurorehabilitation. The project, titled "Targeted Repair of Neural Pathways with Focused Ultrasonic Waves," aims to create a noninvasive technology capable of modulating neural connectivity between two brain regions to repair...
- Federal Grant Award Summary The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded $2.0 million to the University of Illinois on August 15, 2025, for the "Biocomputing and Learning with Synthetic and Biological Oscillators on Spatial Architectures" project, with a completion date of July 31, 2029. The award supports research inspired by the brain's auditory perception capabilities, specifically the cocktail party problem—the human nervous system's ability to...
- Federal Grant Award Summary The National Science Foundation's Division of Electrical, Communications and Cyber Systems awarded $285,380 to the University of Maryland Baltimore County under the Engineering program (CFDA 47.041) beginning September 1, 2025, with completion by May 31, 2026. This project grant supports research and development of high-resolution transcranial ultrasound (HR-TUS) neuromodulation technology utilizing orthogonal crossed ultrasound beams to achieve unprecedented...
- Federal Grant Award Summary The University of Illinois received a $300,000 Project Grant from the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering program (CFDA 47.041) to conduct collaborative research on the foundations of super-linearization. Awarded August 1, 2025, with completion targeted for July 31, 2028, this three-year initiative delivers research products and services focused on transforming nonlinear dynamical...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems awarded $200,000 to the University of Massachusetts on June 15, 2025, under the Engineering program (CFDA 47.041) for a project titled "Closed-Loop Hybrid Intelligence with Optogenetic-Neuromorphic Co-Designed Cell Interfaces." The project, scheduled for completion by May 31, 2028, delivers advanced engineering tools and methods that integrate high-resolution...
- Federal Grant Award Summary Northwestern University received a $3.0 million Project Grant from the National Science Foundation's Engineering program (CFDA 47.041), effective April 1, 2026, through March 31, 2029. This NSF Trailblazer initiative supports fundamental research investigating non-electrical mechanisms of neuronal excitation to advance brain-computer interface (BCI) and neuroengineering technologies. The primary research deliverable involves the development of biocompatible, synthetic...
- Federal Project Grant Award Summary The National Science Foundation's Engineering program (CFDA 47.041) awarded $199,991 to the University of Michigan-Dearborn on May 15, 2026, through an Engineering Research Initiation (ERI) grant to develop a novel microphysiological system that models perivascular environments in the brain. The primary deliverable is an engineered device that replicates cerebrospinal fluid (CSF) flow dynamics and cellular conditions while enabling precise control over...
The University of Illinois received a $395,787 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), awarded May 1, 2026, with completion targeted for April 30, 2029. The primary deliverable is an innovative laboratory tool that applies precisely controlled mechanical forces to individual neurons using light-driven technology, enabling researchers to study how ultrasound-based neuromodulation affects brain cells at the nanoscale. The tool combines a gold nanostructure that converts light into localized sound waves with a highly sensitive microscope capable of measuring minute forces, allowing independent adjustment of force parameters including strength, timing, frequency, and duration to replicate ultrasound stimulation characteristics. This research initiative aims to advance understanding of mechanical neuromodulation mechanisms at the cellular level, with direct applications toward developing safer and more effective brain therapies for treating neurological disorders. The project incorporates an educational component designed to foster interest in bio-inspired photonics and neuroscience among future generations of scientists and engineers, aligning with the Engineering program's emphasis on advancing innovation while building a skilled engineering workforce. By systematically measuring neuronal responses to well-defined mechanical stimuli, the research will provide critical insights to inform the development of next-generation healthcare biotechnologies.Federal Project Grant Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $395.8k | 4/30/26 |