This $337,422 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) aims to develop a novel "neuron-to-neuron interface" that can transmit signals between individual neurons in the brains of two zebrafish larvae. The researchers at the University of Illinois seek to create a system that allows synchronized behavioral outputs in both a "sender" and "receiver" fish by transmitting neural signals optically between their...
The National Science Foundation (NSF) is providing a $170,617 Project Grant under its Engineering program (CFDA 47.041) to the University of Illinois to advance the scientific study of brain functional changes after a stroke and pioneer a tailored rehabilitation strategy that fits each individual's needs. The 5-year project aims to combine different imaging methods to guide electrical brain stimulation that improves the recovery of movement for stroke patients, potentially benefiting over half a...
This $329,099 federal Project Grant award was provided by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CFDA 47.070) program. The grant aims to develop new computational models to uncover the functional architecture of the brain and its role in enabling complex behaviors like navigation and decision-making. Specifically, the project will: Identify the brain systems underlying navigation in zebrafish larvae using advanced optical imaging...
The National Science Foundation (NSF) awarded a $512,275 Project Grant to the University of Utah to develop a focused ultrasound system for the noninvasive repair of damaged neural pathways. The project, funded under NSF's Engineering program (CFDA 47.041), aims to create a therapeutic tool that can modulate neural connectivity in the human brain, with the potential to enable rehabilitation for individuals affected by neurological and mental health conditions. The research team, comprising an...
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $434,716 to the University of Oklahoma Health Sciences Center to develop a set of optical tools for capturing and interpreting high-speed recordings of neural activity across the entire zebrafish brain. The key objectives are to create fluorescent voltage sensors, optical microscopes, and signal processing algorithms that can simultaneously monitor millisecond-scale bursts of neural...
This National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Carnegie Mellon University (CMU) provides $500,000 in funding from July 1, 2024 to June 30, 2027 to develop a new computational framework for predicting neuron growth and transport regulation in biological neural circuits (BNCs). The project aims to advance knowledge of the fundamental mechanisms of neural growth, material transport regulation, and circuit dynamics through three specific objectives: (1)...
This $1.5 million Project Grant from the National Science Foundation (NSF), under the Engineering federal grant program (CFDA 47.041), will fund research at the University of California Irvine from October 2022 through September 2026. The university will develop hydrogel-based bioengineering technologies to reproducibly generate distinct spatial organization and cellular diversity within cortical organoids, mimicking the development of different brain regions. Researchers will leverage expertise...
The National Science Foundation (NSF) Engineering Directorate awarded a $564,510 Project Grant to the University of Massachusetts (UMass) to develop an engineered neural organoid system with improved brain regionalization and integrated mesh electrodes for enhanced monitoring and stimulation capabilities. The key objectives of this 3-year grant project are to: 1) Assemble regionalized neural organoids that enable thalamus-subpallium-cortex projections by stacking sliced organoids, 2) Innervate...
This Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) provides $283,596 to the University of California, Irvine to develop conformable, expandable neural interface devices that can monitor brain activity as animals transition to performing complex cognitive behaviors. The goal is to identify neurophysiological signatures of emerging cognition and improve understanding of how brain circuits form to support...
This federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $630,000 to the University of Chicago to develop a new technology called the Monolithic Adjustable Photostimulation (MAP) platform for high spatiotemporal photostimulation of the nervous system. The project aims to create minimally-invasive, optically-controlled neuromodulation devices using advanced silicon heterojunctions that can precisely stimulate neural circuits, with the goal...