This SBIR Phase I award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $273,550 to Biocognon LLC for the development of a combinatorial platform to discover improved molecular recognition components for use in therapeutic and diagnostic antibodies. The project aims to utilize synthetic biology, next-generation DNA sequencing, and computational biology to efficiently generate and screen libraries of antibody...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award supports the development of a novel device that can rapidly and automatically extract pathogen DNA from whole blood samples to enable faster diagnosis of sepsis. The $274,858 award to New England Hemolytics, Inc., with a project period from September 1, 2024 to February 28, 2025, will fund the testing and optimization of this technology across common sepsis-causing pathogens. The...
This National Science Foundation (NSF) Project Grant award under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $274,362 to RT Microdx Inc., a small business based in Brookline, MA, to develop a molecular diagnostic platform for detecting respiratory diseases like strep throat. The platform aims to provide laboratory-quality accuracy for in-home use without requiring an expensive tabletop device. The key technical objectives include optimizing the sensitivity...
This National Science Foundation (NSF) Cooperative Agreement award under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $1,250,000 in funding to Micropure Genomics Inc., a minority-owned small business located in Middletown, Delaware. The project aims to develop an innovative, automated platform for preparing high-quality DNA samples to support long-read sequencing technologies. The platform will streamline sample preparation, reducing time, cost, and...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $303,445 to Endura Therapeutics Inc. aims to develop a next-generation sequencing platform for discovering small molecules that target RNA. The project addresses two key challenges: demonstrating that small molecules binding to messenger RNA can modulate protein expression in cells, and developing a high-throughput screening method to identify such molecules and their optimal...
The National Science Foundation (NSF) awarded a $275,000 SBIR Phase I grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Om Therapeutics Inc. in La Jolla, CA. The goal of this project is to enable the discovery of new medicines at an unprecedented rate by empowering researchers to launch drug discovery programs quickly and cost-effectively. The innovation involves the ability to screen billions of unique small molecules against the entire human proteome in a...
Pathotrak LLC received a $884,848 cooperative agreement award from the National Science Foundation on December 15, 2021 to complete work by November 30, 2023. The award is part of NSF's Technology, Innovation, and Partnerships program (CFDA 47.084) to advance science, engineering, and technology solutions. Specifically, the funding supports Pathotrak's SBIR Phase II project to develop rapid detection methods for pathogens in manufacturing trimmings. The company will work to deliver technology...
This $270,128 SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a low-cost, field-use DNA-based rapid diagnostic device for detecting plant diseases. The project aims to create a user-friendly, battery-operated testing kit that allows farmers to quickly identify diseases like citrus greening in their fields, enabling early intervention and more sustainable farming practices. The 9-month...
This Project Grant award of $305,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a transformative diagnostic platform by Resonantia Diagnostics, Inc. The platform aims to rapidly identify pathogens and determine their antimicrobial susceptibility within 60 minutes directly from patient samples. By enabling fast, evidence-based treatment decisions at the point of care, this innovation has the potential...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $331,189 to develop a new, affordable virus detection technology. The project aims to integrate protein engineering and electrochemical biosensors to create a portable, room-temperature stable platform for virus detection in resource-limited environments. Key components include engineered enzymes for isothermal nucleic acid amplification and an...