Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of an autonomous, miniaturized system for DNA extraction and preparation for sequencing. The $275,000 award to Anyglabs, Inc. will fund the creation of a portable, automated device capable of high-throughput DNA processing in space and other austere environments. The goal is to democratize access to advanced molecular...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant of $274,932 awarded to Femtofluidics Incorporated aims to develop hardware that can rapidly and inexpensively synthesize DNA-encoded libraries (DELs) to accelerate drug discovery. The project proposes a novel approach to combinatorial chemistry using an electronic substrate that can manipulate nanoliter-to-picoliter volume droplets without any...
Sequegenics LLC received a $251,073 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant supports development of low-cost and scalable methods for creating genomic databases using long-read next-generation DNA sequencing technologies. This aligns with the program's goals of fostering innovation in engineering research. The one-year project period runs from August 1, 2021 through July 31,...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) is providing $275,000 to Dinya DNA Inc. to support the commercial development of a novel DNA synthesis technology. The key products or services being delivered include: Developing new methods to ensure higher fidelity DNA precursors, which are the building blocks for DNA synthesis Reducing synthesis costs by streamlining the DNA synthesis reactions...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program award provides $274,990 to Dencoda LLC to develop a novel DNA-based kinase assay platform. The key products to be delivered are: A highly sensitive, specific, and multiplexed kinase activity assay that can be used as a research tool to discover new therapeutic targets or as a clinical diagnostic test for diseases involving kinase dysregulation, such as cancers, diabetes, and Alzheimer's disease....
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
Under a $997,781 cooperative agreement awarded by the National Science Foundation (NSF) through its Technology, Innovation, and Partnerships (CFDA 47.084) program, Nanopath Inc. - a woman-owned small business - is developing an integrated point-of-care system for rapid pathogen identification and characterization. The system utilizes proprietary nanosensor technology to detect target nucleic acid sequences directly from patient samples, eliminating the need for bacterial culture or nucleic...
This $976,771 Cooperative Agreement awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program will support Biomesense Inc., a for-profit biotechnology company, in the development of a novel measurement platform to enable large-scale, longitudinal studies of the gut microbiome. The key products to be delivered through this project include: (1) refinement of processes for capturing and storing microbial RNA from gut samples, (2)...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Cellecho, Inc. aims to develop a microchip-based technology for advanced cell engineering. The key products and services to be delivered under this award include: The proposed microchip technology will leverage sound waves and electric fields to precisely manipulate cells and sequentially deliver customizable combinations of genetic materials such as DNA, mRNA, and...