Project Grant 2443910
- The National Science Foundation (NSF) awarded a $500,001 Project Grant under the Biological Sciences (CFDA 47.074) Federal Grant Program to the University of New Mexico (UNM). The grant supports pioneering research in large-volume optical microscopy using pupil-matched remote focusing (PMRF) techniques. The project will develop advanced microscope systems that enable fast, high-resolution, and label-free imaging of large biological samples. Key activities include educational and outreach...
- This National Science Foundation (NSF) Project Grant award under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 in funding to Nanores LLC for the development of a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues at nanoscale resolution and depths up to 250 micrometers. The project aims to advance fluorescence imaging capabilities to enable breakthroughs in drug discovery, disease...
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences program (CFDA 47.074) to the Georgia Institute of Technology in the amount of $861,467 starting on September 1, 2025 and ending on August 31, 2028. The purpose of the grant is to enable research and educational infrastructure innovations in biophotonics and advanced microscopy. The research goal is to develop and implement Parallel Multifocal Scanning Microscopy (PMS), a super-resolution imaging technique...
- The National Science Foundation (NSF) awarded a $630,000 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to the University of New Mexico (UNM) to develop an advanced optical microscopy system. The project aims to significantly improve the study of protein clustering and interactions on cell membranes, which could advance the understanding of cell signaling and related diseases like cancer. The highly interdisciplinary research will combine the MINFLUX and modal...
- The University of Texas Health Science Center at Houston was awarded a three-year, $704,556 Project Grant from the National Science Foundation Division of Biological Infrastructure under the Biological Sciences federal grant program (CFDA 47.074). The grant will support the development of random field-based approaches to spatially analyze tissue architecture and heterogeneity using spatial transcriptomics and single-cell RNA sequencing data. Key products include a computational toolset called...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $174,112 project grant to Trustees of Tufts College to develop a photonic-integrated-circuit two-photon (PIC-2P) microscopy system. This system aims to enable deeper tissue imaging and faster, larger-volume cell observations compared to conventional two-photon microscopy. The project focuses on advancing nanophotonic chip technologies to overcome the depth limitations of two-photon microscopy, which is used to...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $275,989 Project Grant to William Marsh Rice University in Houston, TX. The grant, with a project period from March 1, 2025 to February 28, 2030, aims to develop advanced tools to visualize, quantify, and correlate DNA dynamics, organization, and gene activity in human cells with unprecedented resolution. The project will apply innovative labeling strategies, 3D nanoscale imaging, and...
- The Massachusetts Institute of Technology (MIT) has been awarded a 5-year, $487,873 National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant to develop advanced label-free microscopy technologies for deep-tissue biological imaging. The project aims to create innovative fiber optic light sources, excitation methods, and algorithmic reconstruction techniques to enable label-free multiplex imaging that can visualize dynamic cellular processes within living tissue with...
- This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging...
- This National Science Foundation project grant award of $299,323 provides funding for research services at the University of Oklahoma from April 15, 2022 through March 31, 2024. The award is made through the Integrative Activities program (CFDA 47.083), which supports activities to build STEM capacity and broaden participation in research. Specifically, the award will fund the development of a novel mesoscopic imaging technique to investigate functional neuronal connections in the mouse...
The National Science Foundation (NSF) Biological Sciences Federal Grant Program (CFDA 47.074) awarded a $303,958 Project Grant to the University of Texas at Austin for a five-year period from August 2025 to July 2030. The grant will support the development of novel methods for deep-tissue optical imaging using inverse-scattering techniques to computationally decode light scattering in biological tissue. The project aims to extend optical imaging depths by an order of magnitude, enabling large-scale 3D imaging of intact or in-vivo samples. The developments will also be applied to other wave-based regimes affected by scattering, such as acoustics, lidar, and X-rays. Additionally, the project will create a modular and low-cost "LegoCellScope" platform to train students on computational imaging theory and application, which will be integrated into local school curricula.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $304.0k | 7/29/25 |