The National Science Foundation (NSF) Engineering program awarded a $695,746 CAREER grant to The Washington University's Office of Sponsored Research Services Division to support research aimed at understanding how to grow more mature heart muscle from induced pluripotent stem cells (iPSCs) in the laboratory. The research project will investigate how combining mechanical loading and changes in energy sources can enhance the electrical maturation of iPSC-derived cardiomyocytes to better predict...
This National Science Foundation Project Grant of $419,750 will fund research at Washington University in St. Louis from August 1, 2022 to July 31, 2025 to study how living cells move across dissimilar physical environments and retain mechanical memories of prior environments. Specifically, the award will integrate experiments and computational modeling to examine how forces generated by cells modify their surroundings in two mechanically different environments during migration. This will reveal...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $467,202 project grant to the Research Foundation of the City University of New York (RFCUNY) to develop an intelligent lab-on-chip device that can non-invasively monitor the maturation of stem cell-derived cardiomyocytes in real-time and apply adaptive biophysical stimulation to promote full cell maturation. The interdisciplinary research team from RFCUNY, City College of New York, and Rutgers University plans...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports research studying living tissues as new types of adaptive materials. The $285,570 award, effective Sep 1, 2025 through Aug 31, 2030, will investigate how cellular adaptability influences the mechanical behavior of tissues. The research aims to create a link between cellular biology and material properties, providing insights into disease treatment and inspiring the design of new...
The National Science Foundation (NSF) awarded a $763,083 Faculty Early Career Development (CAREER) grant to the Regents of the University of Michigan under the Engineering program (CFDA 47.041) to support fundamental research on "Informed Testing - From Full-Field Characterization of Mechanically Graded Soft Materials to Student Equity in the Classroom". The 5-year project aims to establish a method to both cause and quantify 3D deformations inside designed soft materials, reducing the...
The National Science Foundation awarded a $890,510 project grant to Virginia Commonwealth University under the Engineering federal grant program (CFDA 47.041) for research titled "BIOMECHANICS OF LEADER CELLS." The five-year award, issued February 1, 2022 with a completion date of January 31, 2027, will support research into the biomechanics of leader cells. The NSF's Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in...
The National Science Foundation (NSF) awarded a 5-year, $574,881 CAREER grant to The Washington University's Office of Sponsored Research Services Division to investigate the biomechanical consequences of localized defects in the aortic wall. The research aims to better understand the factors that contribute to aortic rupture using innovative mechanobiological, microstructural, and mechanical testing approaches. Specific objectives include a comprehensive biomechanical assessment of aortic...
The National Science Foundation awarded a $609,605 Project Grant to the University of Missouri System under the Engineering program (CFDA 47.041) for the period of April 1, 2021 through March 31, 2026. The grant funds the CAREER: FINITE ELASTICITY OF MORPHING METAMATERIALS. THEORY AND APPLICATIONS project. This project will support the development of theoretical and applied research on finite elasticity of morphing metamaterials. The Engineering program seeks to improve quality of life and...
This Project Grant from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation provides $511,901 to Purdue University from September 2021 through July 2025. The award supports research titled "CAREER: REGULATION OF HYALURONAN PRODUCTION AND FUNCTION BY BIOMECHANICAL SIGNALS" under the NSF Engineering Program (CFDA 47.041). The NSF Directorate for Engineering seeks to improve quality of life and economic strength by fostering innovation and...
This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) is supporting a collaborative research effort focused on developing an intelligent lab-on-chip device to monitor and promote the maturation of stem cell-derived cardiomyocytes. The $192,150 award to the New York Institute of Technology (NYIT) aims to create an integrated system that can non-invasively evaluate cardiomyocyte maturity in real-time and adaptively apply electrical and mechanical...