Project Grant 2440375

Award Date 9/1/25
Completion Date 8/31/30
Dollars Obligated $286K
Funding Federal Agency
Office of Integrative Activities
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Burlington, VT 05405, USA
Similar Awards
This $400,000 Project Grant awarded by the National Science Foundation (NSF) under CFDA Program 47.041 "Engineering" will support a collaborative research effort between Cornell University and Swiss partners to develop an integrated mechanobiology framework for engineering the shape and internal architecture of biological tissues. The key goals of the project are to: 1) use computational design tools to guide robotic micromanipulation in order to uncover the mechanical principles...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award supports a research project titled "CAREER: Advancing In Vivo Knowledge and Assessment of Cartilage Material Properties with Quantitative MRI" at the University of Vermont & State Agricultural College. The $624,622 award, spanning September 1, 2025 to August 31, 2030, aims to improve scientific understanding of the relationship between the microscopic structure and macroscopic function of...
This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
This National Science Foundation (NSF) Project Grant award, under the Engineering program (CFDA 47.041), provides $283,237 to North Carolina State University (NC State) to conduct fundamental research on how ultra-soft inclusions, such as cells and cell-like particles, interact with fiber networks and affect the overall deformation behavior of the host material. The goal is to gain new insights into the design and fabrication of bio-inspired, adaptive materials for applications in smart...
This Project Grant award, valued at $314,769.00, was provided by the National Science Foundation's Engineering program (CFDA 47.041) to the University of Delaware. The award will support research to develop new platforms based on magnetic materials that can be locally stiffened in time with precise control over location, in order to mimic different biological events and explore how mechanobiological signaling is transduced via communication between cells away from a region of local stiffness...
This federal Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports research to quantify the mechanical forces inside living cells and determine how changes in these forces impact cellular behavior. The $160,000 award to Boise State University, with a project period from February 1, 2025 to January 31, 2028, aims to develop predictive tools that use mechanical forces to control cell behavior, enabling advances in tissue engineering,...
This $635,000 Project Grant awarded by the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation supports research to understand how mechanical boundary conditions influence tissue assembly and repair in 3D fibrous microtissues. The research aims to advance knowledge about the mechanisms by which mechanical forces regulate new tissue formation and organization, particularly as it relates to wound healing. The project will integrate in vitro experiments and...
The National Science Foundation awarded a $996,596 Project Grant to The Regents of the University of Colorado under the Engineering federal grant program (CFDA 47.041) to establish a framework for modeling the mechanical behavior of living building materials for structural applications from August 1, 2022 to July 31, 2027. Specifically, the award will support research to develop a new multiscale cellular and granular material poroelastic formulation for a microbial precipitation-based living...
This National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences project grant for $300,000 aims to engineer shape-morphing materials as cell sheet culturing substrates to develop human tissues with controllable shape, cellular composition, and morphology. The 3-year project, beginning on September 1, 2023, will use thermoresponsive hydrogels to enable cell sheet expulsion and explore how material characteristics impact stem cell fate. Additionally, the project seeks...
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $199,982 to Wesleyan University to investigate the principles governing the interactions at the interface between different groups of cells. The research aims to understand how cells from different tissues interact and organize themselves when they come into contact, which is crucial for processes like tissue development, wound healing, and cancer metastasis. The project will use...

This Project Grant award of $285,570 from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports research at the University of Vermont & State Agricultural College investigating living tissues as new types of adaptive materials. The project aims to study how cellular adaptability influences the larger-scale mechanical behavior of tissues, connecting cellular biology and material properties. It will develop a new adaptive tissue model to integrate biological and soft matter physics perspectives, producing experimentally testable and clinically relevant predictions for tuning tissue-level mechanical properties. The findings are expected to advance the understanding of biological processes like wound healing and cancer invasion, while also inspiring the development of bio-mimetic materials with self-healing and adaptable properties. This 5-year award, which commenced on September 1, 2025, does not involve any sub-awards.

Generated 8/5/25, 4:23 AM