This Project Grant award, totaling $805,374.00, is funded by the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program. The primary focus of this 5-year research project, awarded to Rutgers, The State University, is to uncover the fundamental principles governing how cells sense and respond to mechanical forces at their surface. By investigating mechanosensitive membrane proteins, such as Piezo channels, the project aims to establish a thermodynamic framework for understanding mechanosensing at the subcellular level. This multifaceted approach will generate comprehensive insights into cell migration, tissue homeostasis, and touch sensation, potentially leading to applications in therapeutic development for various mechanobiological diseases. The project will also incorporate interdisciplinary education through integrated teaching, mentoring, and outreach activities to benefit students at multiple levels.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $805.4k | 7/1/25 |