This $668,494 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will fund research to systematically identify and characterize non-canonical open reading frames (ORFs) in four model plant species: Arabidopsis, tomato, rice, and maize. The project aims to discover undetected ORFs that can reveal new ways plants use proteins and control gene activities, offering opportunities to improve crop performance. Key activities include integrating...
This $998,790 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support enhancing global plant transformation capacity through research, training, and partnerships led by Boyce Thompson Institute For Plant Research Inc. Over a three-year period, the grantee will establish a global research coordination network to collectively address challenges to plant genetic engineering and gene editing efficiency. The network aims to facilitate...
This federal Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,000,000 to Cold Spring Harbor Laboratory (CSHL) for a project titled "Unlocking the Genetic and Epigenetic Basis of Cereal Crop Adaptation to Acidic Soil Regions." The project aims to identify genetic and epigenetic mechanisms that contribute to aluminum (Al) tolerance in major cereal crops like maize and sorghum, which is crucial for improving crop...
This federal Project Grant award of $1,192,499.00 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research by the Donald Danforth Plant Science Center in Missouri to develop epigenetic editing tools for crop improvement.
The key objectives of this 4-year project are to: 1) Expand epigenetic editing technologies to other crop species beyond cassava, such as rice and tomato, to enable disease resistance; 2) Demonstrate additional applications of...
This $314,560 Project Grant award from the National Science Foundation (NSF) Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074) supports collaborative research by Purdue University to develop crop varieties that enhance agricultural sustainability. The key objectives are to:
Identify genetic targets underlying microbiome-mediated genetic resistance to major current and emergent biotic and abiotic stresses in three widely-grown crops - wheat, tomato, and...
This $299,988 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of unique synthetic circular DNA molecules called "synplasomes" to enable more efficient plant genome editing and engineering. The research aims to create self-replicating plant episomes that can be delivered via nano-enabled transformation methods to enhance transgene expression levels and duration in diverse plant species, including tobacco,...
This National Science Foundation (NSF) Project Grant, funded under the Biological Sciences program (CFDA 47.074), aims to advance fundamental knowledge on the engineering of plant minichromosomes for synthetic biology applications. The $993,190 award, effective from November 1, 2024 to October 31, 2028, supports research at the University of Maine focused on developing methods to construct stable and transmissible plant minichromosomes. The goal is to create programmable extrachromosomal DNA...
This $794,457 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will develop new tools for geneticists to incorporate emerging models of genetics into their research and rigorously test the underlying concepts. The project will leverage laboratory plants and crops as test systems to develop and validate these genetic analysis tools, which will better incorporate molecular and cellular biology knowledge into statistical models for gene...
This $720,557 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to characterize the epigenetic reprogramming that occurs during the transition from gametes (egg and sperm) to the zygote in plants. The primary focus is on elucidating the genome-wide epigenetic modifications in rice, an important crop plant, though methods will first be optimized in the model plant Arabidopsis. The project aims to generate a comprehensive...
This Project Grant award, funded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074), supports research to develop new methods for improving plant transformation and regeneration, with a focus on maize. The $959,997 award, effective January 1, 2025 through December 31, 2027, will be conducted by the Cold Spring Harbor Laboratory (CSHL), a renowned non-profit research institution. The project aims to provide a better understanding of the molecular mechanisms...