This $699,870 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports the development of simplified and highly efficient genetic modification technologies for economically important grasses and cereal crops. The "PLANTTRANSFORM: SMART GRASS" project aims to overcome the current constraint in the plant science research community regarding the capacity to genetically modify major crop plants. The award establishes a...
This $959,997 federal Project Grant, awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074), supports collaborative research at the Cold Spring Harbor Laboratory to develop improved methods for plant transformation and regeneration. The research aims to provide a thorough understanding of the molecular mechanisms underlying regeneration in maize, a key crop that provides a substantial portion of human caloric intake. By exploiting a "morphogenic-based"...
This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
The National Science Foundation (NSF), through its Office of International Science and Engineering (CFDA 47.079), awarded a $2,298,366 project grant to the University of Illinois - Urbana Champaign to fund the "Global Centers: Alliance for Socially-Acceptable & Actionable Plants" (ASAP) initiative. This multi-national partnership project aims to leverage natural biodiversity and advanced technologies like artificial intelligence and synthetic biology to engineer high-energy,...
This $524,852 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at Virginia Polytechnic Institute & State University (Virginia Tech) to develop improved methods for plant transformation and regeneration in maize and other recalcitrant crop species. The project aims to provide a comprehensive understanding of the molecular mechanisms underlying plant regeneration through the use of morphogenic factors, with the goal of...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $464,968 project grant to the Boyce Thompson Institute for Plant Research Inc. This 3-year REU site grant, effective April 15, 2024, will support the training of 30 undergraduate students from underrepresented backgrounds in plant genome research at the Boyce Thompson Institute on the Cornell University campus. The students will develop interdisciplinary skills in data analysis, bioinformatics, experimental...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program grant of $1,346,558.00 awarded to the National Center For Genome Resources (NCGR) in Santa Fe, New Mexico will develop functional pangenomic and machine learning tools to explore genetic diversity in plants. The project aims to connect different versions of plant genes with successful growth in varying climate conditions, revealing which gene variants plants will need as the climate changes. The goal is to create...
This $1,999,998 National Science Foundation Project Grant, funded under the Biological Sciences program (CFDA 47.074), supports research at the University of Washington to advance plant synthetic biology through deciphering the grammar of crop gene regulatory elements. The three-year award beginning March 1, 2023 will apply massively parallel reporter assays and machine learning to characterize tens of thousands of genetic regulatory elements in maize and tomato, including enhancers,...
This $1,211,545 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) will support the development of advanced Prime Editing (PE) systems in rice, tomato, and poplar plants. Prime Editing is a novel and highly versatile CRISPR-based gene editing technology that enables precise genome modifications. The key objectives of this 3-year project are to optimize Prime Editor proteins to increase their activity and editing efficiency, improve pegRNA structure and...