This $432,740 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the Cal Poly Corporation supports the development of a new class of paper-based chronometric biosensors. The objective is to create quantitative point-of-care diagnostic tools that can detect a range of biological analytes, including disease markers, environmental contaminants, and security threats, using time as the sensing signal. The novel biosensors will leverage polymer degrading enzymes to achieve high sensitivity comparable to more complex laboratory tests, while maintaining the simplicity and low cost of lateral flow immunoassays. This research could enable the rapid, widespread deployment of quantitative, easy-to-use diagnostics to address critical health and security needs. The 3-year project will also provide undergraduate research opportunities at Cal Poly University.
Generated 8/13/24, 2:23 AM