This Project Grant award, provided by the National Science Foundation's Mathematical and Physical Sciences (MPS) Directorate, will support research by Professor Reynolds and his students at Campbell University to study the application of thiamine diphosphate-dependent enzymes for sustainable chemical synthesis. The $250,000 award, with a period of performance from September 1, 2024 to August 31, 2026, will enable the exploration of these enzymes for the stereoselective formation of α-substituted ketones, which are important precursors to more complex, bioactive compounds. The research aims to expand the scope of reactions available to thiamine-dependent enzymes, making them more broadly useful for chemical synthesis. This work also promotes the retention of diverse talent in STEM fields through research and mentoring opportunities for underrepresented students.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $250.0k | 7/9/24 |