This $336,380 federal Project Grant from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports research to develop a three-dimensional computational model of leaf development. The project aims to characterize the structural diversity of plant leaves, simulate how this variation influences leaf performance, and inform the design of self-assembling, biomimetic materials. Key objectives include: (1) developing new image analysis methods to analyze 3D cell and tissue...
The National Science Foundation (NSF) awarded a $100,000 CAREER grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside (UC Riverside) to develop a multiscale mathematical model for understanding the mechanisms underlying cell morphogenesis and tissue development in plant leaves. The 5-year project aims to improve understanding of the general principles that govern cell shape formation and tissue growth, using the interdigitated...
This National Science Foundation (NSF) Biological Sciences program project grant to Yale University is focused on advancing understanding of stomatal regulation and photosynthesis in plants. The $258,877 award, running from February 2024 to January 2027, will employ a new laser-based technique to directly measure guard cell turgor pressure and elucidate the mechanisms controlling stomatal opening and closing across diverse plant lineages. This research aims to reveal fundamental biophysical...
This $171,697 project grant from the National Science Foundation's Mathematical and Physical Sciences program aims to advance understanding of biophysical mechanisms that generate reproducible organ shapes during development. Specifically, the grant supports research by Cornell University and partners in France to elucidate how plant leaves maintain flatness as they grow. The collaborative project titled "The Biophysical Basis of Flat Organ Morphogenesis from Fluctuating Cellular...
This Project Grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation provides $270,040 to Florida International University under the Engineering program (CFDA 47.041) from October 1, 2022 to November 30, 2026. The funding will support research and education focused on developing plant-inspired composite materials using cellulose and bioinspired interfaces. Specifically, the awardee will conduct multiscale computational modeling and experimental...
This $735,000 project grant awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at Cornell University to investigate the functional interactions of plant transcription factors that regulate the three-dimensional patterning of grass leaves. The research aims to understand the mechanisms by which the LG1 and WOX3 transcription factors coordinate leaf width, length, and angle, which directly impact photosynthesis and leaf morphology in maize. The...
The National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) awarded a $451,667 Project Grant to Virginia Polytechnic Institute & State University (Virginia Tech) to conduct fundamental research on creating plant-inspired growing robots capable of long-duration monitoring missions in complex, dynamic environments. The research aims to develop robotic hardware and capabilities that mimic plant-like "growth" and adaptation, enabling real-time and long-term...
This $400,000 Project Grant awarded by the National Science Foundation (NSF) under CFDA Program 47.041 "Engineering" will support a collaborative research effort between Cornell University and Swiss partners to develop an integrated mechanobiology framework for engineering the shape and internal architecture of biological tissues. The key goals of the project are to: 1) use computational design tools to guide robotic micromanipulation in order to uncover the mechanical principles...
The National Science Foundation awarded $564,893 under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program to the University of Wisconsin-Madison to develop a chemically defined, plant-derived biomaterial platform for human cell culture from September 1, 2022 to August 31, 2025. The award will support research to decellularize plant leaf material for use as a broadly useful and adaptable biomaterial for human cell culture. Researchers will characterize the chemical...
This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...