Project Grant 2401861
Award Date
9/1/24
Completion Date
8/31/27
Dollars Obligated
$547K
Funding Federal Agency
Office of Integrative Activities
Awarding Federal Agency
Division of Chemical, Bioengineering, Environmental, and Transport System
Federal Grant Program
47.083
Assistance Type
Project Grant
Place of Performance
Princess Anne, MD 21853, USA
Similar Awards
The National Science Foundation (NSF) Office of Integrative Activities awarded a $738,400 Project Grant to the Morehouse School of Medicine (MSM) to investigate the synergistic effects of engineered extracellular vesicles (EVs) from stem cells and macrophages on angiogenesis, the formation of new blood vessels. The 4-year project will explore how EVs from different cell types cooperatively regulate normal and pathological angiogenesis, as well as develop novel EV-based therapeutic strategies....
This $483,492 Project Grant awarded by the National Science Foundation's Engineering program to the University of Maryland, College Park, aims to develop biomaterial tools for investigating how extracellular matrix (ECM) ligands influence the function of macrophage immune cells. The 5-year project will leverage polyethylene glycol-based biomaterials with known peptide-derived ECM ligands to quantify the impact of ECM ligand-integrin receptor interactions on macrophage activation. The research...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $601,071 Project Grant to Texas A&M Engineering Experiment Station (Tees), a division of the Texas A&M University System, to conduct research under the NSF Engineering program (CFDA 47.041). The goal of this 3-year project is to develop a predictive mathematical model of the relationship between bone morphogenetic protein (BMP) signaling and stem cell differentiation...
This National Science Foundation (NSF) Project Grant under CFDA Number 47.041 - Engineering provides $360,000 in funding to Cornell University from July 1, 2023 to June 30, 2026 to develop a novel biosensing platform for the simultaneous detection and quantification of exosomes (small vesicles released from cells) and their molecular cargo. The key objectives are to: (1) develop methods to capture, quantify, and profile exosomes using a plasmonic biosensor; (2) develop techniques to lyse the...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), is supporting research to develop mitochondrial-targeting exosomes (MTEs) containing anti-inflammatory microRNAs (MTE-miRNAs) to treat neuroinflammation. The $469,500 award to Michigan Technological University aims to restore mitochondrial function, reduce oxidative stress,...
This $140,314 National Science Foundation project grant under the Integrative Activities program (CFDA 47.083) will fund research and training related to exosome proteomics analysis and biomarker discovery for cancer diagnostics. Louisiana Tech University will collaborate with the University of Houston to identify glioblastoma-specific protein biomarkers in exosomes purified from biofluids using disease-specific surface markers. The Principal Investigator and one graduate student will receive...
This $349,999 Project Grant, awarded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), aims to create a new biomaterial platform that can precisely control the composition and stiffness of the extracellular matrix (ECM) to investigate how these factors influence airway basal stem cell (BC) self-renewal and differentiation. The interdisciplinary research combines expertise in materials science, stem cell biology, and regenerative medicine to develop an advanced...
This $508,785 federal Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports research at Columbia University to investigate how the chemical composition and mechanical properties of biomaterials can be optimized to improve the production and function of T cells for use in cancer immunotherapy. The project aims to gain fundamental knowledge on how nutrient transport, particularly oxygen availability, within these biomaterials affects T cell...
This $500,000 National Science Foundation project grant supports research to advance the biom anufacturing of extracellular vesicles through the integration of human induced pluripotent stem cell technology, genome engineering, and membrane nanofabrication. The primary recipient is Syracuse University, with Rochester Institute of Technology serving as a sub-awardee. Under the Biological Sciences program (CFDA 47.074), the grantees will work to generate a stable human iPSC line with enhanced EV...
This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering. Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage repair....