Project Grant 2349832
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $488,204 Project Grant to the University of Texas at Austin under the Biological Sciences federal grant program (CFDA 47.074) with a completion date of June 30, 2025. The grant supports research using epitranscriptomics to study how chemically-induced changes in RNA molecules within biological cells in response to environmental stressors can be used to track and control stress responses. An interdisciplinary...
- This three-year Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences totals $1,512,792 to fund research at Louisiana State University examining the gene regulatory networks affected by purine catabolites in bacterial pathogens. The research aims to identify additional transcription factors in Burkholderia thailandensis responsive to urate and xanthine, which accumulate in host tissues during infection due to production of reactive oxygen species....
- The National Science Foundation (NSF) awarded a $919,999 Project Grant under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This 3-year grant, beginning September 1, 2023, supports research to investigate the evolution and functional role of small regulatory RNAs (sRNAs) in diverse bacterial lineages, particularly those living symbiotically within pest insect hosts. The project aims to determine how sRNA sequence divergence and...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $414,164 Project Grant under the Biological Sciences CFDA program to the University of Illinois at Chicago. This 3-year grant, awarded on August 15, 2023, will support research to study how enzymes in intermediary metabolism interact with and bind to RNA molecules. The project aims to gain a greater understanding of these protein-RNA interactions and their effects on regulating cellular activities,...
- This $299,779 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research at Louisiana State University from August 2022 to July 2024 to design an RNA-based dual regulator for repetitive gene expression regulation. The research integrates biological experiments and computational studies to train scientists and engineers in interdisciplinary research. It also aims to cultivate a multidisciplinary perspective for problem-solving. Specifically, the...
- This Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences, under the Biological Sciences CFDA program (47.074), will investigate a novel regulatory mechanism called "RNA buffering" that maintains messenger RNA (mRNA) levels despite changes in synthesis and decay rates. The $749,978 project at the University of Utah will explore the protein-protein and protein-RNA interactions involved in this process, which challenges...
- Federal Project Grant Award Summary The University of Texas at Austin received a $1,028,700 Project Grant award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective September 1, 2025, with a completion date of August 31, 2028. This research project investigates the biophysical mechanisms of transbilayer coupling by protein condensates—a newly discovered cellular communication mechanism in which...
- This $849,713 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to elucidate RNA-RNA interaction networks during interbacterial interactions involving the bacterium Pseudomonas aeruginosa. The research team at Boston Children's Hospital seeks to define the small RNA (sRNA) interaction network in P. aeruginosa and decode the regulatory roles played by sRNAs during its interactions with other bacteria. The project will...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,299,732 to the University of Texas at Austin under a Project Grant to support research titled "COLLABORATIVE RESEARCH: SYNTHETIC AND SYSTEMS BIOLOGY APPROACHES TO SEMI-SYNTHETIC CELLS WITH EXPANDED DNA ALPHABETS." The three-year award beginning August 15, 2021 falls under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and strengthen the Nation's...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences and Division of Mathematical Sciences awarded a $550,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Texas at Austin. The grant, titled "COLLABORATIVE RESEARCH: MODULUS: PROTEIN DROPLETS DRIVE MEMBRANE BENDING AND CYTOSKELETAL ORGANIZATION," seeks to improve understanding of how protein droplets interact with cellular membranes and the cytoskeleton. The...
This National Science Foundation (NSF) Biological Sciences program award to the University of Texas at Austin provides $650,195 over 3 years to investigate regulatory mechanisms used by RNA-binding proteins within a bacterial central carbon metabolism network. The researchers will use experimental and computational tools to: (i) explore the formation of bacterial condensates as a post-transcriptional gene regulation mechanism, and (ii) elucidate dynamic regulatory outcomes from alternative usage of regulatory binding sites. This work aims to advance fundamental understanding of sophisticated native gene control schemes in bacterial systems and develop novel control mechanisms more aligned with natural cellular metabolism. The project also includes research opportunities for students from underrepresented communities and a course development component.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.2k | 3/20/24 |