The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $757,389 Project Grant to the University of Texas at Austin to support research titled "Understanding Highly Heterogeneous Biological Membranes" from August 1, 2021 through July 31, 2024. This award will fund research into major problems confronting the nation through advancing the biological sciences, as outlined in the Biological Sciences program (CFDA 47.074). Specifically, the University of...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded $1,299,732 to the University of Texas at Austin under a Project Grant to support research titled "COLLABORATIVE RESEARCH: SYNTHETIC AND SYSTEMS BIOLOGY APPROACHES TO SEMI-SYNTHETIC CELLS WITH EXPANDED DNA ALPHABETS." The three-year award beginning August 15, 2021 falls under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and strengthen the Nation's...
This National Science Foundation (NSF) CAREER award under the Biological Sciences (CFDA 47.074) program provides $242,103 to the Massachusetts Institute of Technology (MIT) to investigate how proteins and lipids coordinate the formation and function of membrane-associated condensates. The research aims to advance the understanding of cell surface organization, which could lead to breakthroughs in biotechnology, disease treatment, and improving overall knowledge of cell communication and...
The National Science Foundation (NSF) Division of Chemistry awarded a $500,000 Project Grant titled "TOPICS IN PROTEIN AND RNA FOLDING AND DYNAMICS" to the University of Texas at Austin under the Mathematical and Physical Sciences program (CFDA 47.049). This 4-year grant will support Professor Devarajan Thirumalai's research on the computational modeling of protein and RNA interactions and dynamics. Key focus areas include developing new methods to simulate intrinsically disordered...
The National Science Foundation awarded a $538,838 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to The Regents of the University of California, San Francisco for research titled "Collaborative Research: Mapping Protein-Membrane Interactions from Molecules to Cell-Level Dynamics." The research will develop multiscale models to map how individual protein structures and compositions interact with and deform cell membranes at varying scales, from...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded $508,806 under the Biological Sciences (CFDA 47.074) federal grant program to the Regents of the University of Michigan for a collaborative research project titled "Mechanics of Reconstituted Self-Organized Contractile Actomyosin Systems." The project aims to advance understanding of cytoskeletal network self-organization and force generation through reconstituting actin networks and contractile...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $785,201 Project Grant to The Regents of the University of Colorado to support research titled "Collaborative Research: Understanding Protein Mechanical Stability and Its Impact on Secretion." The two-year grant running from January 15, 2022 to December 31, 2024 will fund research under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $206,912 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of North Carolina at Chapel Hill. The three-year grant, effective August 1, 2023 through July 31, 2026, supports collaborative research to enhance the understanding of protein structures and behaviors at extreme temperature and pressure conditions. The research aims to develop rules for predicting protein...
The National Science Foundation (NSF) awarded a $166,667 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Texas Health Science Center at Houston (UTHealth). This 3-year grant, effective May 1, 2024, supports interdisciplinary research to decipher the composition, architecture, and mechanism of the gliding motility machinery in bacteria. The project employs cutting-edge techniques like cryogenic electron microscopy and fluorescence microscopy...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Virginia Polytechnic Institute and State University a $297,204 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period of August 1, 2021 through July 31, 2023. The grant funds research titled "EAGER: TOPOGRAPHICALLY INDUCED LATERAL ORGANIZATION IN BIOMIMETIC LIPID MEMBRANES" to promote progress in the biological sciences and increase understanding of major...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences and Division of Mathematical Sciences awarded a $550,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Texas at Austin. The grant, titled "COLLABORATIVE RESEARCH: MODULUS: PROTEIN DROPLETS DRIVE MEMBRANE BENDING AND CYTOSKELETAL ORGANIZATION," seeks to improve understanding of how protein droplets interact with cellular membranes and the cytoskeleton. The research aims to shed light on fundamental mechanisms that organize soft matter and have implications for understanding pathogen invasion, endocytic processes, and cellular motility. The project combines theoretical, computational, and experimental methods to study the mechanical functions of protein condensates at the interface between membranes, cytoskeletal filaments, and liquid droplets. The three-year grant period runs from September 1, 2023 to August 31, 2026.