This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $200,000 to Oakland University aims to develop a novel low-cost, wireless 3D ultrasound imaging system for use in low-resource settings. The key goals are to: 1) establish quantitative tools using signal processing and artificial intelligence to extract ultrasound-derived biomarkers for improved breast cancer diagnosis, and 2) develop a robust calibration, registration, and sensor fusion protocol to...
The National Science Foundation (NSF) awarded a $406,900 Project Grant under the Engineering (CFDA 47.041) program to Texas A&M Engineering Experiment Station (Tees) to develop large-scale optical ultrasound transducer (OUT) arrays for high-speed and high-resolution 3D acoustic tomography. The project aims to create a new optical technology that can detect and convert acoustic wave fields into optical signals, enabling improved performance and reduced cost for 3D ultrasound imaging...
This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging...
This $295,000 National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award to Sonovance, Inc. is for the development of low-cost hardware and software to enable the acquisition of high-quality ultrasound images by non-expert operators. The innovation focuses on novel signal and image processing methods that can accurately reconstruct ultrasound data from freehand 2D scans, even with imperfect information on the probe position. This enables...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation...
The National Science Foundation (NSF) awarded a $199,940 Project Grant to Bucknell University under the Engineering (CFDA 47.041) program. The grant supports research to investigate the effects of low-frequency, low-intensity ultrasound on the interaction between endothelial cells and macrophages, which is important for understanding the biological mechanisms behind the use of ultrasound therapy to promote wound healing. The research aims to characterize how ultrasound affects the pro-angiogenic...
This $840,292 federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program aims to advance a transformative three-dimensional (3D) ultrasound imaging technology. The research objective is to conduct use-inspired research to overcome technical challenges and knowledge gaps, making the 3D imaging technique ready for commercial ultrasound market adoption. The proposed project will improve device components to enhance imaging...
This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) provides $199,930 to the University of Chicago to assess microbubble-induced stresses on soft materials like tissue, in order to support the development of regulatory guidelines for bubble-based medical devices like therapeutic ultrasound systems. The key objectives are to: 1) develop and characterize a mechanophore-based tissue phantom to quantify microbubble-induced deformation, 2)...
The National Science Foundation (NSF) awarded a $500,000 Project Grant to the University of California, San Diego (UCSD) under the Engineering (CFDA #47.041) program to design, fabricate, and evaluate acoustic-to-optical nanoscale transducers. The goal of this 3-year project is to develop novel micro-auscultation devices that can efficiently convert weak sound waves into optical signals, enabling the detection and interpretation of acoustic signatures from small biological objects like cells,...
The National Science Foundation (NSF) awarded a $568,480 Project Grant under the Engineering (CFDA 47.041) program to The Regents of the University of Colorado, doing business as the University of Colorado, to conduct research on a novel biosensing concept for high-sensitivity measurement of cell mechanical biomarkers. The 3-year award, effective May 1, 2024, will investigate how biological cells with different mechanical properties interact with acoustic waves propagating along a substrate, and...