The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $200,000 to Oakland University aims to develop a novel low-cost, wireless 3D ultrasound imaging system for use in low-resource settings. The key goals are to: 1) establish quantitative tools using signal processing and artificial intelligence to extract ultrasound-derived biomarkers for improved breast cancer diagnosis, and 2) develop a robust calibration, registration, and sensor fusion protocol to...
The National Science Foundation (NSF) has awarded a $266,856 Project Grant to the San Diego State University Research Foundation under the NSF Engineering program (CFDA 47.041) for the period of May 1, 2024 to April 30, 2027. The grant aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation dynamics to understand how microbubble clusters can be used to navigate through blood vessels. The research team will...
This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) provides $199,930 to the University of Chicago to assess microbubble-induced stresses on soft materials like tissue, in order to support the development of regulatory guidelines for bubble-based medical devices like therapeutic ultrasound systems. The key objectives are to: 1) develop and characterize a mechanophore-based tissue phantom to quantify microbubble-induced deformation, 2)...
This National Science Foundation (NSF) Project Grant under the Engineering program (CFDA 47.041) awarded $200,000 to Lawrence Technological University (LTU) to develop integrated non-contact ultrasound generation and detection systems. The project aims to enable high-resolution, non-contact tissue functional imaging and biomechanical characterization, addressing limitations of current ultrasound imaging methods that require direct contact. The research plan focuses on integrating photoacoustic...
The National Science Foundation (NSF) awarded a $437,038 Project Grant under the Engineering program (CFDA 47.041) to the University of Massachusetts (UMass) to develop a technology for targeted electrical stimulation of endothelial cells lining blood vessels. The objective is to modulate endothelial cell function to enhance drug delivery to tumors and improve treatment outcomes for cancer patients. The 5-year project will study pulsed electric field waveforms that can selectively alter...
The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded a $250,000 Project Grant to Northeastern University for research titled "COLLABORATIVE RESEARCH: AN IMPLANTABLE INTRACRANIAL ULTRASOUND STIMULATION FOR TREATING NEURODISEASES." The three-year award beginning August 15, 2021 supports research under the NSF Engineering program (CFDA 47.041) to develop an implantable intracranial ultrasound device for treating neurodiseases. The NSF...
This $200,000 National Science Foundation (NSF) Engineering (CFDA 47.041) Project Grant award to Clarkson University will develop a novel near-infrared (NIR) mechanochemical biophotonic platform for deep-tissue biomedical imaging. The project aims to create a breakthrough technology that combines ultrasound waves and NIR light to enable high-resolution, 3D imaging of molecular and sub-cellular structures deep within the body. This approach seeks to address limitations of existing imaging...
This $350,000 National Science Foundation project grant supports research at the University of Virginia from October 1, 2022 to September 30, 2025 under the NSF Engineering program (CFDA 47.041). The research aims to advance understanding of the effects of microgravity on wound healing processes by leveraging a sensor-integrated 3D tissue culture model. Specifically, the project will explore dynamic changes in gene and protein expression, endothelial network formation, and extracellular matrix...
This $516,762 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports fundamental research at the University of Central Florida (UCF) to develop a new ultrasonic shearing method for scalable manufacturing of uniform-sized nanobubbles. The research aims to advance nanobubble production capabilities, particularly for biomedical applications like drug delivery and medical imaging. Key aspects include computational modeling of the ultrasonic...