The National Science Foundation (NSF) awarded a $500,000 Project Grant to the University of California, San Diego (UCSD) under the Engineering (CFDA #47.041) program to design, fabricate, and evaluate acoustic-to-optical nanoscale transducers. The goal of this 3-year project is to develop novel micro-auscultation devices that can efficiently convert weak sound waves into optical signals, enabling the detection and interpretation of acoustic signatures from small biological objects like cells,...
This $600,120 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program supports the development of a groundbreaking microfluidic-based instrument capable of measuring the mass of individual live cells with picogram-level accuracy and millisecond-scale temporal resolution. The innovative instrument uses small pipettes to gently capture cells and precisely detect mass changes, enabling continuous monitoring of crucial cellular processes...
This $462,332 National Science Foundation project grant supports research into biomechanical regulation of intranuclear elastography and gene location in single cells. The NSF Division of Civil, Mechanical, and Manufacturing Innovation awarded this funding through the Engineering program (CFDA 47.041) to The Regents of the University of Colorado on September 1, 2022 for completion by August 31, 2025. The University of Colorado will conduct fundamental research measuring gene expression and...
The National Science Foundation (NSF) Division of Chemistry awarded a $420,000 Project Grant to the University of Utah from August 1, 2023 to July 31, 2026 under the Mathematical and Physical Sciences program (CFDA 47.049). The funding supports the development of a novel optical biosensor capable of detecting and quantifying a wide range of biological molecules, including biomarkers found in bodily fluids. The project leverages second harmonic generation (SHG) and optical heterodyning techniques...
This National Science Foundation Project Grant of $395,312 will fund the development of shape-encoded electrokinetic particles for multiplexed biosensing through June 2027. Under the NSF Engineering Directorate's CFDA 47.041 program, the University of Colorado Boulder will work to advance biosensing technologies that can detect heterogeneous biomarkers from blood in a single assay. Specifically, the university will study how biomarker size, charge density, and concentration influence the induced...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant, awarded to the University of California, Los Angeles (UCLA) for $600,000.00, aims to develop an innovative Optomagnetic Twisting Cytometry (OMTC) system to quantify the dynamic viscoelastic properties of 3D tissue samples. The project will leverage the OMTC system to advance the understanding of the mechanical properties of live tissues, which play a crucial role in various biological processes. The...
The National Science Foundation (NSF) awarded a $253,890 Project Grant under the Biological Sciences program (CFDA 47.074) to Western University of Health Sciences to conduct research on sensory membrane proteins. The goal is to develop computational tools capable of realistic simulations of how these proteins respond to external stimuli like pressure, heat, and sound. The research project, titled "Collaborative Research: Ultra-Fast Simulations of Sensory Membrane Proteins with Validation...
This $228,697 National Science Foundation award under the Engineering program (CFDA 47.041) will support the development of an optical biosensor technology to facilitate drug screening and validation efforts. Auctus Biologics, Inc. will utilize a proprietary temperature, pH, and chemically stable protein composed of two fragments that bind with antibody-like affinity and specificity. Over the one-year period ending January 2023, the company will establish the technology's suitability for...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation...
The National Science Foundation awarded a $508,000 Project Grant to The Regents of the University of Colorado under the Engineering program (CFDA 47.041) for the period of February 1, 2021 through January 31, 2026. The grant funds the research project "CAREER: DUAL-COMB PHOTOACOUSTIC MICROSCOPY WITH SUPER-RESOLUTION WAVEFRONT SHAPING" which will develop a new dual-comb photoacoustic microscopy technique using super-resolution wavefront shaping to achieve sub-diffraction limited imaging...